Impact of COVID-19 Pandemic on Presentation and Outcome of Consecutive Patients Admitted to Hospital Due to ST-Elevation Myocardial Infarction

Wienbergen, Harm; Retzlaff, Tina; Schmucker, Johannes; Marín, Luis Alberto Mata; Rühle, Stephan; Garstka, Daniela; Osteresch, Rico; Fach, Andreas; Hambrecht, Rainer

doi:10.1016/j.amjcard.2021.04.011

Cited by 14 publications

(21 citation statements)

References 26 publications

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“…The last two years have unexpectedly brought another threat -related to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. As reported by the latest registers from around the world, the incidence of OHCA increased significantly during the pandemic [32,[34][35][36][37][38][39]. Moreover, performed meta-analyzes demonstrated that not only the incidence but also mortality following OHCA were higher during the COVID-19 pandemic [32,33,40].…”

Section: Discussionmentioning

confidence: 97%

Observational, retrospective study evaluating the temporal variability of out-of-hospital cardiac arrests (OHCA) in the district of Bydgoszcz in a 24-month period

Paciorek

Obońska

Skrzyński

et al. 2021

Medical Research Journal

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Introduction: The incidence of out-of-hospital cardiac arrests (OHCA) varies periodically. The aim of our study was to assess the temporal variability of OHCA occurrence in adult population of Bydgoszcz district.Material and methods: A retrospective analysis of 782 cases of OHCA, which occurred between January 1 st , 2018, and December 31 st , 2019, was performed. The temporal variability of OHCA occurrence was assessed during the day (within twenty-four 1-hour periods and four 6-hour time intervals), weeks, months, and seasons of the year. Results:The incidence of OHCA in the analyzed population was 84 per 100,000 inhabitants/year. The highest incidence of OHCA was observed between 08:00 and 08:59 and between 15:00 and 15:59.The lowest number of OHCA occurred at night (n = 84; 10.7%; p < 0.001). During the week, the lowest number of OHCA was noted on Saturday (12.4%) and the highest on Monday (16.5%), with no significant differences between days. The highest incidence of OHCA was observed in winter and the lowest in summer [225 (28.8%) vs. 171 (21.9%), p = 0.006]. December was the month with the highest number of OHCA cases, and July the lowest. Conclusions:The present analysis confirms that the occurrence of OHCA demonstrates circadian, monthly, and seasonal rhythm. The highest incidence of OHCA was in the morning and afternoon, and in winter, especially in December. The lowest occurrence of OHCA was at night and in the summer, particularly in July. There was a weekly pattern with the highest occurrence of OHCA on Mondays; however' no significant differences between weekdays were achieved.

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Section: Discussionmentioning

confidence: 97%

Observational, retrospective study evaluating the temporal variability of out-of-hospital cardiac arrests (OHCA) in the district of Bydgoszcz in a 24-month period

Paciorek

Obońska

Skrzyński

et al. 2021

Medical Research Journal

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“…Wienbergen et al, 17 conducted a study to assess the outcomes of patients with STEMI in the year 2020 compared with the years before in a German registry. They included 726 in year 2020 and compared it to 10,226 patients in the years 2006 to 2019 and found that hospital mortality was elevated by 52% compared with the years prior.…”

Section: Discussionmentioning

confidence: 99%

“…The COVID-19 pandemic and the pandemic-related lockdown and social restriction may have impacted the clinical course of patients treated for acute ST-elevation myocardial infarction (STEMI), although the implications and exact impact are unclear. Information from the database does show, however, that in the year 2020, a highly significant increase of STEMI-patients admitted to hospitals with delayed presentation and poor prognosis was reported 16 , 17 .…”

Section: Introductionmentioning

confidence: 99%

Impact of COVID-19 Pandemic on the Outcomes of Acute Coronary Syndrome

Alharbi¹,

Franz²,

Alfatlawi³

et al. 2023

Current Problems in Cardiology

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“…They discussed a possible delay by patients, medical services or cardiac catheterization laboratories. Furthermore, Wienbergen et al [ 18 ] showed a significantly higher rate of patients presenting with cardiogenic shock and out-of-hospital cardiac arrest. That may be associated with a delayed presentation in the case of STEMI and may also have contributed to the increased in-hospital mortality demonstrated in our study.…”

Section: Discussionmentioning

confidence: 99%

COVID-19 pandemic affects STEMI numbers and in-hospital mortality: results of a nationwide analysis in Germany

et al. 2022

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Background The COVID-19 pandemic led to extensive restrictions in Germany in 2020, including the postponement of elective interventions. We examined the impact on ST-elevation myocardial infarction (STEMI) as an acute and non-postponable disease. Methods Using German national records, all STEMI between 2017 and 2020 were identified. Using the number of STEMI cases between 2017 and 2019, we created a forecast for 2020 and compared it with the observed number of STEMI in 2020. Results From 2017 to 2020, 248,062 patients were treated for STEMI in Germany. Mean age was 65.21 years and 28.36% were female. When comparing forecasted and observed STEMI in 2020, a correlation can be seen: noticeable fewer STEMI were treated in those weeks respectively months with an increasing COVID-19 hospitalization rate (monthly percentage decrease in STEMI: March − 14.85%, April − 13.39%, November − 11.92%, December − 22.95%). At the same time, the crude in-hospital mortality after STEMI increased significantly at the peaks of the first and second waves (relative risk/RR of monthly in-hospital mortality: April RR = 1.11 [95% CI 1.02; 1.21], November RR = 1.13 [1.04; 1.24], December RR = 1.16 [1.06; 1.27]). Conclusion The COVID-19 pandemic led to a noticeable decrease in the number of STEMI interventions in Germany at the peaks of the first and second waves in 2020, corresponding to an increase in COVID-19 hospitalizations. At the same time, in-hospital mortality after STEMI increased significantly in these phases. Graphical abstract Impact of the COVID-19 pandemic on STEMI numbers and in-hospital mortality in Germany. Relative difference between forecasted and observed STEMI numbers (above figure), the relative risk of in-hospital mortality (middle figure) as well as number of new hospital admissions for COVID-19 per million inhabitants according to Roser et al.27 (bottom figure).

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Impact of COVID-19 Pandemic on Presentation and Outcome of Consecutive Patients Admitted to Hospital Due to ST-Elevation Myocardial Infarction

Cited by 14 publications

References 26 publications

Observational, retrospective study evaluating the temporal variability of out-of-hospital cardiac arrests (OHCA) in the district of Bydgoszcz in a 24-month period

Observational, retrospective study evaluating the temporal variability of out-of-hospital cardiac arrests (OHCA) in the district of Bydgoszcz in a 24-month period

Impact of COVID-19 Pandemic on the Outcomes of Acute Coronary Syndrome

COVID-19 pandemic affects STEMI numbers and in-hospital mortality: results of a nationwide analysis in Germany

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