Impact of dietary polyphenols on neuroinflammation-associated disorders

Revi, Neeraja; Rengan, Aravind Kumar

doi:10.1007/s10072-021-05303-1

Cited by 13 publications

(3 citation statements)

References 147 publications

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“…Curcumin inhibited gelation of IL-1, TNF-, vasodilators E2, peroxynitrite, inducible NO glucanase, and Lipoxygenase in vitro experiments (Kang et al, 2022). Crocin (a carotenoid), oral dosages (an alkaloid), scutellarin (a flavone), but also anthocyanins a flavanone-7-O-glycoside are phenolic acids affiliated with predicament properties (Revi and Rengan, 2021). In patients, a 1 g numerous times oral mouthful of Rosuvastatin, a SIRT1 activator, reduced the matrix process is driven, raised myocyte interleukins, IL-4, but also fibroblast economic expansion (FGF)-2, and inevitably energized host defenses (Hao et al, 2022).…”

Section: Neuro-inflammationmentioning

confidence: 99%

Tea polyphenols: extraction techniques and its potency as a nutraceutical

Shaukat

Ali

Yang

et al. 2023

Front. Sustain. Food Syst.

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Usually, polyphenols help address numerous health issues caused by oxidative stress. Tea is a popular beverage (rich in polyphenols) with abundant health promoting and disease prevention with great health-promoting and disease-prevention attributes, originating from the delicate, dried leaves of the Camellia sinensis plant. Tea has been proven to have health-boosting impacts like anti-inflammatory, anti-cancerous, anti-diabetic, and aids in weight loss. Cognitive impairment, also known as cognitive decline caused by aging or other neurological disorders, has become an emerging health concern. Tea polyphenols, especially phenolic acids, havegained enormous attention due to their link to improved cognitive function by preventing cognitive decline. This review summarizes recent studies on the health benefits of polyphenols in tea. Additionally, effective traditional and modern techniques to extract polyphenols and their effects on various diseases have been described.

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Section: Neuro-inflammationmentioning

confidence: 99%

Tea polyphenols: extraction techniques and its potency as a nutraceutical

Shaukat

Ali

Yang

et al. 2023

Front. Sustain. Food Syst.

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“…The neuroprotective effect of adzuki beans is probably dependent on the polyphenols and saponins in adzuki beans. Indeed, the neuroprotection of polyphenols (Revi & Rengan, 2021) and saponins (Oyeleke & Owoyele, 2022) has been evidenced.…”

Section: Health Benefits Of Adzuki Bean and Its Componentsmentioning

confidence: 99%

Adzuki bean (Vigna angularis): Chemical compositions, physicochemical properties, health benefits, and food applications

Zou

et al. 2022

Comp Rev Food Sci Food Safe

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Adzuki bean (Vigna angularis), also called red bean, is a legume of Fabaceae (Leguminosae) family. This crop is native to East Asia and is also commercially available in other parts of the world. It is becoming a research focus owing to its distinct nutritional properties (e.g., abundant in polyphenols). The diverse health benefits and multiple utilization of this pulse are associated with its unique composition. However, there is a paucity of reviews focusing on the nutritional properties and potent applications of adzuki beans. This review summarizes the chemical compositions, physicochemical properties, health benefits, processing, and applications of adzuki beans. Suggestions on how to better utilize the adzuki bean are also provided to facilitate its development as a functional grain. Adzuki bean and its components can be further developed into value‐added and nutritionally enhanced products.

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“…BDNF plays a role in neuronal growth, differentiation, neuronal survival, synaptic plasticity, and memory and learning processes [ 16 , 17 ]. Human and animal studies have demonstrated that acute exercise bouts stimulate neuronal function, brain vascularization, and neurogenesis, improve mood, and enhance learning [ 18 , 19 ] via the elevation of BDNF [ 18 , 19 , 20 , 21 , 22 , 23 ]. Conversely, exercise in polluted air has been shown to inhibit the acute exercise-induced increase in BDNF secretion typically seen following exercise bouts, suggesting that exposure to air pollution blunts the improvement in cognitive health and CNS plasticity [ 18 , 19 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

The Effects of Polyphenol Supplementation on BDNF, Cytokines and Cognition in Trained Male Cyclists following Acute Ozone Exposure during High-Intensity Cycling

Morton,

Paton,

Braakhuis

2024

Nutrients

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The neurotoxic effects of ozone exposure are related to neuroinflammation and increases in reactive oxygen species (ROS). This study aimed to assess inflammation, Brain-Derived Neurotrophic Factor (BDNF), and cognition in healthy male cyclists following polyphenol supplementation and exercise in an ozone-polluted environment. Ten male cyclists initially completed a maximal incremental test and maximal effort 4 km time trial in ambient air. Cyclists then completed two trials in an ozone-polluted environment (0.25 ppm) following 7 days of supplementation with either polyphenol (POLY) or placebo (PL). Experimental trials consisted of a three-stage submaximal test followed by a 4 km time trial. Blood samples were drawn pre- and post-exercise, and analyzed for BDNF, interleukin 6 (IL-6), interleukin 10 (IL-10) and tumor necrosis factor (TNF-α). The Stroop test and serial subtraction task were performed before ozone exposure and again after the 4 km TT. Serum BDNF increased post-exercise (p < 0.0001), and positive differences were observed post-exercise in the ozone POLY group relative to PL (p = 0.013). Plasma IL-6 increased post-exercise (p = 0.0015), and TNF-α increased post-ozone exposure (p = 0.0018). There were no differences in Stroop or serial subtraction tasks pre- or post-exercise. Exercise increases BDNF in ozone.

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Impact of dietary polyphenols on neuroinflammation-associated disorders

Cited by 13 publications

References 147 publications

Tea polyphenols: extraction techniques and its potency as a nutraceutical

Tea polyphenols: extraction techniques and its potency as a nutraceutical

Adzuki bean (Vigna angularis): Chemical compositions, physicochemical properties, health benefits, and food applications

The Effects of Polyphenol Supplementation on BDNF, Cytokines and Cognition in Trained Male Cyclists following Acute Ozone Exposure during High-Intensity Cycling

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