Impact of Different Variables on Recovery Time in Patients Receiving Hemodialysis

Abstract

Introduction.Patients on hemodialysis (HD) are proven to have impaired Health Related Quality of Life (HRQoL) compared to the general population. Recovery from the hemodialysis session is a permanent problem among majority of patients receiving HD treatment. A partial explanation may be the osmotic imbalance between different compartments of the body due to the fluid and electrolyte movement across the cell membrane which is a part of the HD process itself. The aim of our study was to see whether the length of recovery time (RT) is associated with different clinically relevant variables and dialysis treatment features in our HD population. Methods. We performed a cross-sectional study on patients receiving trice weekly HD in a single hemodialysis center. The recovery time was defined by posing a single question "How long does it take you to recover after a hemodialysis session?" and was calculated in hours (up to 2, 2-6, 6-12, and 12-24 hours) / minutes. Various demographic and clinical characteristics were analyzed for association with the RT. Results. The mean RT was 364.62±339.24 minutes. From all of the analyzed variables a significant statistical correlation was obtained with the level of albumin, urea, interdialytic weight gain (IDWG), protein catabolic rate (PCR), body mass index (BMI) and the level of hemoglobin (p<0.05 for all parameters). The longest mean RT had patients with hypertension and glomerulonephritis as a primary cause of ESRD and the shortest, patients with an adult dominant polycystic kidney disease. With the multiple regression analysis a significant correlation was obtained only for the level of hemoglobin (Hb) with a coefficient for partial regression analysis -0.2635. The t-test showed that the influence of the level of hemoglobin on recovery time in patients was statistically significant (p = 0.039). Conclusions. RT in our study was associated with IDWG, albumin, urea, BMI, and PCR, while the level of hemo-

Do biochemical parameters and intradialytic symptoms affectpost‐dialysisrecovery time? A prospective, descriptive study

“…Some studies reported correlations between a few biochemical or hematological factors and recovery time [25,26]. However, other studies reported no significant relationship between Kt/V, URR, and albumin, creatinine, calcium, and Hb levels with recovery time, which was similar to our findings [7,8,27,28]. We found that the Kt/V, URR, and Hb values of most participants (Kt/V ≥ 1.4, URR ≥70%, and Hb level ≥ 11 g/ dL were found in 65.5%, 60.5%, and 54.7% of the participants respectively of the participants respectively) were within the recommended limits posted in the guidelines [29,30].…”

Dialysis recovery time: associated factors and its association with quality of life of hemodialysis patients

“…We demonstrated that malnutrition was associated with a prolonged DRT. We found a significant negative correlation between serum albumin level and the DRT (rs = − 0.143, p = 0.048), which is similar to the findings of Smokovska et al [32] who reported that a shorter DRT was associated with a higher serum albumin level. On the other hand, Bossola et al [6] found no significant correlation between serum albumin level and the DRT; however, they explained this by stating that all cases were managed till target albumin levels according to the KDOQI guidelines.…”

“…We found a negative significant correlation between the DRT and age (rs = − 0.179, p = 0.013), which is in line with the findings of Fitzpatrick et al [33] and Yoowannakul et al [34]. Other studies revealed no association between these variables [14,32,35,36]. It is possible that the shorter recovery durations recorded by elderly individuals are associated with patients' greater satisfaction and lower expectations despite having poorer clinical profiles.…”

“…Many other studies reported similar results [ 47 , 48 ]. However, Smokovska et al [ 32 ] found a strong negative association between the Hb level and the post-HD recovery time. In our study, no correlation was found between serum calcium and the DRT, which is in line with the findings of McCann et al [ 49 ] and Bossola et al [ 6 ], who reported that patients’ phosphorus levels were not associated with fatigue.…”

Waktu Pulih Pascahemodialisis

“…Terdapat beberapa studi yang menemukan bahwa kadar serum albumin dapat mempengaruhi waktu pulih pascahemodialisis (Hussein et al, 2017;Rayner et al, 2014). Parameter biokimia lain yang juga dapat mempengaruhi waktu pulih adalah kadar ureum serum (r = -0,309; p = 0,003), kadar hemoglobin (r = -0,412; p = 0,0001) dan PCR (r = -0,241; p = 0,017) (Smokovska, Grozdanovski, & Spasovski, 2015). Lebih lanjut, hemoglobin ditemukan sebagai prediktor dominan terhadap waktu pulih pascahemodialisis.…”