Impact of Fermenting Agents on Marketed Patent Proprietary Formulation Ashwagandha Kalpa

Thakur, Ambika; Thakur, Renuka; Baghel, Dileep Singh

doi:10.22159/ajpcr.2017.v10s4.

Cited by 3 publications

(1 citation statement)

References 1 publication

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“…The obtained molar conductance values were in the range of 0.000153-0.000157 Mhos cm 2 mol -1 which designate the non-electrolytic nature of complexes [27]. Also the diamagnetic nature [28] of La(III) complexes were confirmed from the magnetic susceptibility measurements employing diamagnetic corrections (Table-1). The electronic absorption study in UV-visible region was carried out in dimethylformamide solution with 10 -3 M concentration (Table-2).…”

Section: Characterization Of Ternary Complexes Of Lanthanummentioning

confidence: 56%

Some Mixed Ligand Complexes of Lanthanum(III) Using 1-Nitroso-2-napthol and Amino Acids

Thakur¹,

Dhaigude²,

Patil³

2018

Asian J. Chem.

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This work describes the synthesis of three new mixed ligand ternary complexes of La(III) having the general formula [M(1N2N)2·(L)·2H2O] by employing 1-nitroso-2-naphthol (1N2N) primary ligand and L-valine, L-serine, L-isoleucine as secondary ligand. The complexes were characterized by thermal analysis, elemental analysis, electrical conductance, UV-visible spectrum and magnetic susceptibility measurement study. The non-electrolytic nature of the complexes was confirmed by molar conductance studies. Furthermore, the magnetic susceptibility study at room temperature showed that the lanthanum(III) complexes were diamagnetic in nature. Electronic absorption studies of the complexes also show intra-ligand and LMCT transitions, respectively. FT-IR studies confirmed the bonding between the metal ion and ligands via N-and O-donor atoms. The presence of coordinated water molecules was confirmed by thermal study. Additionally, these complexes were tested for antibacterial study by using agar cup and tube dilution method. All the complexes show moderate to good antibacterial activity.

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Section: Characterization Of Ternary Complexes Of Lanthanummentioning

confidence: 56%

Some Mixed Ligand Complexes of Lanthanum(III) Using 1-Nitroso-2-napthol and Amino Acids

Thakur¹,

Dhaigude²,

Patil³

2018

Asian J. Chem.

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Pharmacognostical Study and Analytical Standardization of Bhringaraja Taila: An Ayurvedic Oleaginous Medicine

Kumar,

Singh,

Kumar

et al. 2024

JNR

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Background: Bhringaraja Taila is an Ayurvedic classical formulation. The formulation is indicated as keshaya. The present study is structured around validating the fact of preparing the formulation with and without the addition of mineral (Gairika). Aim: The objectives of this study were to prepare and analyze Bhringaraja Taila. Method: After performing the murchanna samsakara, a specified amount of Drava, Kalka and Sneha dravyas were taken and subjected to moderate heating till the watery portion evaporated Bhringraja Taila prepared with and without Gairika. Results: The refractive index of Bhringraja Taila with and without the addition of Gairika was found to be decreased in both samples. The specific gravity and saponification values of both samples were found to be within the limit but slightly increased in the sample prepared with the addition of Gairika. The iodine value of both samples was found to be less than the limit. A decreased iodine value signifies less tendency toward rancidity. The acid value of both samples was found to be within the limit but more in the sample prepared with the addition of Gairika. The peroxide value of the sample prepared with the addition of Gairika was higher than the sample prepared without Gairika. Higher peroxide value indication of rancidity. The pH of the sample prepared with the addition of Gairika was found to be acidic and the sample prepared without the addition of Gairika was found to be basic. Conclusion: Thus considering the above fact it can be concluded that the formulation was prepared without mineral (Gairika) can be more stable but the therapeutic efficacy between the two formulation cannot be confirmed until and unless there is clinical validation.

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Pharmaceutical Standardization and Comparative Study of Varunadi Kvatha Churna as Varunadi Ghana Vati/Tablet and Varunadi Pravahi Kvatha

Singh,

Chaudhary,

Sharma

et al. 2024

JNR

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Background: In Ayurveda, there are many types of potent dosage forms available with their different specifications, anupan, preparation procedure and shelf life. The preparation of medicines of herbal drug origin is generally included in the Bhaishajya Kalpana section. In Bhaishajya Kalpana there are five basic dosage forms necessary to prepare formulations from herbal origin drugs i.e. Swarasa, Kalka, Kvatha, Hima and Phanta. These five basic formulations are potent dosage forms which can moulded into different finished formulations. Aim: The objectives of this study were to prepare and standardise the Varunadi Kvatha Churna as Varunadi Ghana Vati/Tablet and Varunadi Pravahi Kvatha with a comparative study. Methods: Firstly, kvatha churna was prepared as per the master formula. The kvatha churna was then used in two different ways i.e. firstly it was used to prepare Varunadi Ghana Vati (Tablet) without using any additives as it acts as a self-binder. On the other hand, Pravahi kvatha was prepared which is a self-generated alcohol formulation, in which dhataki pushpa, gudda and babool are added as a fermentation initiator and additives. Results: Physicochemical parameters do not show significant variation. According to the TLC profile, the Ghana Vati has six spots i.e. having much more active constituents than the Pravahi kvatha having two spots. Therefore, according to the parameters, it might be stated that the Pravahi kvatha has much more stability than the Ghana Vati. But as far as palatability and activity are concerned Ghana Vati is comparatively better than Pravahi kvatha Conclusion: Converting Varunadi Kvatha Churna into Varunadi Ghana Vati, Varunadi Pravahi Kvatha provides several benefits related to ease of use, dosage precision, and patient preference. Hence based on observation we stated that the Varunadi Ghana Vati has a better choice of dosage form as compared to Varunadi Pravahi Kvatha, although it has better stability.

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Impact of Fermenting Agents on Marketed Patent Proprietary Formulation Ashwagandha Kalpa

Cited by 3 publications

References 1 publication

Some Mixed Ligand Complexes of Lanthanum(III) Using 1-Nitroso-2-napthol and Amino Acids

Some Mixed Ligand Complexes of Lanthanum(III) Using 1-Nitroso-2-napthol and Amino Acids

Pharmacognostical Study and Analytical Standardization of <i>Bhringaraja Taila</i>: An <i>Ayurvedic</i> Oleaginous Medicine

Pharmaceutical Standardization and Comparative Study of <i>Varunadi Kvatha Churna</i> as <i>Varunadi Ghana Vati</i>/Tablet and <i>Varunadi Pravahi Kvatha</i>

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