Impact of Five Nights of Sleep Restriction on Glucose Metabolism, Leptin and Testosterone in Young Adult Men

Reynolds, Amy; Dorrian, Jillian; Liu, Yang; Dongen, Hans P A Van; Wittert, Gary; Harmer, Lee J.; Banks, Siobhan

doi:10.1371/journal.pone.0041218

Cited by 195 publications

(160 citation statements)

References 79 publications

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“…Among the studies that did find an increase in leptin levels, one measured the energy balance of the subjects and found energy balance to be positive during sleep loss in comparison to after habitual sleep [25]. Leptin increased in parallel with increase in energy intake and energy expenditure [25], while other studies either reported no significant differences in energy intake [42, 45, 52] or did not evaluate energy expenditure [44]. Among studies that reported no significant difference in leptin, some did not assess energy intake or controlled calorie intake [33, 46, 51] while others reported increase in calorie intake without any changes in energy expenditure [47, 49, 50].…”

Section: Sleep Loss and Its Role In The Development Of Cardiometabmentioning

confidence: 99%

Association between sleep deficiency and cardiometabolic disease: implications for health disparities

Rangaraj

Knutson

2016

Sleep Medicine

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Cardiometabolic diseases, which include obesity, diabetes, hypertension and cardiovascular disease, are associated with reduced quality of life and reduced life expectancy. Unfortunately, racial/ethnic and socioeconomic disparities in these diseases exist such that minority populations, such as African Americans and Hispanics, and those of lower socioeconomic status, experience a greater burden. Several reports have indicated that there are differences in sleep duration and quality that mirror the disparities in cardiometabolic disease. The goal of this paper is to review the association between sleep and cardiometabolic disease risk because of the possibility that suboptimal sleep may partially mediate the cardiometabolic disease disparities. We will review both experimental studies that have restricted sleep duration or impaired sleep quality and examined biomarkers of cardiometabolic disease risk, including glucose metabolism and insulin sensitivity, appetite regulation and food intake, and immune function. We will also review observational studies that have examined the association between habitual sleep duration and quality and the prevalence or risk of obesity, diabetes, hypertension and cardiovascular disease. Many experimental and observational studies do support an association between suboptimal sleep and increased cardiometabolic disease risk.

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Section: Sleep Loss and Its Role In The Development Of Cardiometabmentioning

confidence: 99%

Association between sleep deficiency and cardiometabolic disease: implications for health disparities

Rangaraj

Knutson

2016

Sleep Medicine

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“…55 Similar findings have been found in other experimental studies. 56,57 Sleep quality measures, including sleep latency and non-restorative sleep, have also been linked to metabolic and autonomic changes which have been associated with cardiovascular disease and hypertension. 17,58 The relationship among cardiovascular changes, neuroendocrine changes, and sleep disturbance is not as clear.…”

Section: Psychosocial Correlates Of Sleep and Elevated Blood Pressurementioning

confidence: 99%

Sleep and Pregnancy-Induced Hypertension: A Possible Target for Intervention?

Haney

Buysse²,

Okun³

2013

Journal of Clinical Sleep Medicine

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Sleep disturbances in the general population are associated with elevated blood pressure. This may be due to several mechanisms, including sympathetic activation and hypothalamic-pituitary-adrenal (HPA) axis disturbance. Elevated blood pressure in pregnancy can have devastating effects on both maternal and fetal health and is associated with increased risk for preeclampsia and poor delivery outcomes. Preliminary evidence suggests that mechanisms linking sleep and blood pressure in the general population may also hold in the pregnant population. However, the effects of disturbed sleep on physiologic mechanisms that may directly infl uence blood pressure in pregnancy have not been well studied. The role that sleep disturbance plays in gestational blood pressure elevation and its subsequent consequences warrant further investigation. This review evaluates the current literature on sleep disturbance and elevated blood pressure in pregnancy and proposes possible treatment interventions. T he association between sleep disturbances and elevated blood pressure has been extensively studied in the general population. However, relatively few studies have investigated this relationship in the pregnant population. Pregnancy predisposes women to a variety of sleep disturbances.1,2 Similar to non-pregnant individuals, sleep disturbance in pregnancy may be a risk factor for elevated blood pressure, which can lead to maternal and fetal morbidity . 3,4Gestational hypertension, defi ned as a blood pressure higher than 140/90 diagnosed after 20 weeks of gestation, is associated with fetal growth restriction and abruptio placentae and can predispose to preeclampsia, as well as cardiovascular disease later in lif e. 1,[4][5][6] There are few studies evaluating the link between sleep and blood pressure during pregnancy. In this paper, we fi rst review the relationship between sleep and blood pressure in non-pregnant adults. We then outline factors that predispose pregnant women to poor sleep. We conclude with a review of the emerging literature on the associations between sleep and blood pressure in pregnancy. SLEEP AND BLOOD PRESSURE IN THE NON-PREGNANT POPULATIONIn the U.S. the average sleep duration has decreased by 1.5-2 h/night, with > 30% of Americans sleeping < 6 h/night. 7This phenomenon and the concurrent increase in hypertension intimated a possible link between sleep duration and blood pressure. Recently, a series of epidemiological papers have noted an association between sleep duration (both short and long) and elevated blood press ure [8][9][10][11] ; for example, the Sleep Heart Health Study reported that participants who slept < 5 or ≥ 9 h/night had a greater frequency of hypertension than individuals sleeping

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“…Long practice days, substantial travel, demanding schedules, and game preparations all influence a collegiate-athlete's sleep, nutrition, training, and activity levels outside of their sport of choice, and can have an impact on their overall body composition (3,17,28,32). Although body composition can be reflective of many factors unrelated to elite sport, many recognize that this trait alone can be influential on the performance of elite athletes in competition (1).…”

Section: Introductionmentioning

confidence: 99%

Seasonal Changes in Whole Body and Regional Body Composition Profiles of Elite Collegiate Ice-Hockey Players

Prokop¹,

Reid²,

Andersen³

2016

Journal of Strength and Conditioning Research

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The monitoring of a collegiate hockey player's body composition can reflect fitness characteristics and may help players, coaches, or strength and conditioning specialists optimize physiologic gains during an off-season, whereas simultaneously preventing performance decrements in-season. The purpose of the study was to investigate changes in whole-body and regional-body composition of fat and lean tissue. The body composition profiles of 19 elite Canadian collegiate hockey players were assessed using dual energy X-ray absorptiometry. Players completed end-of-season, preseason, and midseason assessments with questionnaires relating to their off-season and in-season training. Statistically significant changes in body composition profiles were observed between the different time points because players showed various tissue gains and losses depending on the region assessed. Overall, players gained (1.38 kg, p ≤ 0.01) and lost (0.79 kg, p ≤ 0.01) fat tissue during the off-season and in-season, respectively. Players also showed a significant gain of leg lean tissue (0.29 kg, p = 0.02) and loss of arm tissue mass (-0.25 kg, p = 0.02) during the first-half of the competitive season. Several correlations emerged that may provide insight into potential trends that could be more pronounced during longer and more demanding schedules. Collegiate hockey players show changes in body composition during the off-season and in-season. The understanding of body composition profiles, body composition fluctuations, and potential variables that may influence the composition of collegiate hockey players can help coaches and athletic programs tailor their team's training, nutrition, lifestyle, and informative resources to further support their athletes.

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Impact of Five Nights of Sleep Restriction on Glucose Metabolism, Leptin and Testosterone in Young Adult Men

Cited by 195 publications

References 79 publications

Association between sleep deficiency and cardiometabolic disease: implications for health disparities

Association between sleep deficiency and cardiometabolic disease: implications for health disparities

Sleep and Pregnancy-Induced Hypertension: A Possible Target for Intervention?

Seasonal Changes in Whole Body and Regional Body Composition Profiles of Elite Collegiate Ice-Hockey Players

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