Impact of handgrip exercise intensity on brachial artery flow-mediated dilation

Atkinson, Ceri L.; Carter, Howard; Dawson, Ellen A.; Naylor, Louise H.; Thijssen, Dick H. J.; Green, Daniel

doi:10.1007/s00421-015-3157-1

Cited by 33 publications

(39 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The observation of improvement in RH-FMD after a 30 min exposure to shear stress elevated by handgrip exercise is in agreement with some (Atkinson et al, 2015;Tinken et al, 2009) but not all (Gonzales, Thompson, Thistlethwaite, & Scheuermann, 2011) previous observations in young healthy participants. The magnitude of RH-FMD improvement in the 10 min post-intervention trial in the present study (29%) is somewhat lower than previous studies observing FMD improvement [∼51% ) and 76% (Atkinson et al, 2015)].…”

Section: Impact Of the Intervention On Rh-fmdsupporting

confidence: 90%

“…Furthermore, the time course of improvement in RH-FMD was in agreement with Tinken et al (2009), who also reported improvement immediately after the 30 min shear stress elevation intervention, and different from Atkinson et al (2015), who reported improvement 60 min, but not immediately post-intervention. The magnitude of anterograde shear rate created with the intervention in the present study is similar to that reported by Tinken et al (2009), but it is somewhat lower than that of Atkinson et al (2015). The population studied, protocol for RH-FMD and the interventions are similar between studies.…”

Section: Impact Of the Intervention On Rh-fmdsupporting

confidence: 70%

“…The magnitude of RH-FMD improvement in the 10 min post-intervention trial in the present study (29%) is somewhat lower than previous studies observing FMD improvement [∼51% ) and 76% (Atkinson et al, 2015)]. Furthermore, the time course of improvement in RH-FMD was in agreement with Tinken et al (2009), who also reported improvement immediately after the 30 min shear stress elevation intervention, and different from Atkinson et al (2015), who reported improvement 60 min, but not immediately post-intervention. The reason for these discrepancies is not obvious.…”

Section: Impact Of the Intervention On Rh-fmdcontrasting

confidence: 49%

“…This intervention has been shown to result in a significant potentiation of brachial artery RH-FMD (Atkinson et al, 2015). It was performed while participants lay supine with their left arm extended out at an angle of 80 deg with the handgrip dynamometer in their left hand.…”

Section: Handgrip Exercise Interventionmentioning

confidence: 99%

“…Although several studies have reported potentiated brachial artery FMD after acute exposure to an increase in mean shear stress (Ade et al, 2015;Atkinson et al, 2015;Tinken et al, 2009), other investigations have demonstrated an impairment in FMD after intense treadmill or cycling exercise (Birk et al, 2013;Silvestro et al, 2002). Although intense exercise is expected to increase shear stress systemically, it is a complex stimulus that may also increase production of reactive oxygen species Johnson, Padilla, & Wallace, 2012;Silvestro et al, 2002).…”

Section: Haemodynamic Changes and Shear Rate During The Interventionmentioning

confidence: 99%

See 4 more Smart Citations

Thirty minutes of handgrip exercise potentiates flow‐mediated dilatation in response to sustained and transient shear stress stimuli to a similar extent

McPhee

Pyke

2018

Experimental Physiology

View full text Add to dashboard Cite

Brief (30 min) exposure of the brachial artery (BA) to a sustained elevation in shear stress has been shown to potentiate subsequent BA flow-mediated dilatation (FMD) in response to a transient shear stress stimulus [reactive hyperaemia (RH) FMD]. It is unknown whether matching the sustained shear stress exposure to a subsequent sustained shear stress stimulus for FMD [via handgrip exercise (SS-FMD)] might enhance the potentiation of FMD. The purpose of the study, therefore, was to assess the impact of a 30 min handgrip exercise intervention-induced elevation in shear stress on subsequent BA SS-FMD versus RH-FMD. Nineteen healthy men (22 ± 3 years) preformed a 30 min rhythmic handgrip exercise intervention on two experimental days. BA-FMD was assessed using either an RH or a 6 min sustained shear stress stimulus created via handgrip exercise (order of visits counterbalanced) at three time points: pre-intervention and 10 and 60 min post-intervention. The FMD was assessed using duplex ultrasound. Shear stress was estimated as shear rate (SR = BA blood velocity/BA diameter). Data are mean ± SD. Both SS and RH-FMD increased from pre-intervention to 10 min post-intervention [SS-FMD (6 min average), from 0.11 ± 0.05 to 0.16 ± 0.08 mm; P = 0.008; Cohen's d = 0.66; and RH-FMD, from 0.25 ± 0.1 to 0.32 ± 0.11 mm; P = 0.013; Cohen's d = 0.68]. The magnitude of enhancement in RH and SS-FMD did not differ (change in RH versus SS-FMD pre- versus 10 min post-intervention, P = 0.344). These findings suggest that exposure to elevated shear stress via 30 min of handgrip exercise potentiates subsequent FMD in response to sustained and transient elevations in shear stress to a similar extent.

show abstract

Section: Impact Of the Intervention On Rh-fmdsupporting

confidence: 90%

Section: Impact Of the Intervention On Rh-fmdsupporting

confidence: 70%

Section: Impact Of the Intervention On Rh-fmdcontrasting

confidence: 49%

Section: Handgrip Exercise Interventionmentioning

confidence: 99%

Section: Haemodynamic Changes and Shear Rate During The Interventionmentioning

confidence: 99%

See 3 more Smart Citations

Thirty minutes of handgrip exercise potentiates flow‐mediated dilatation in response to sustained and transient shear stress stimuli to a similar extent

McPhee

Pyke

2018

Experimental Physiology

View full text Add to dashboard Cite

show abstract

The influence of vitamin C on the interaction between acute mental stress and endothelial function

et al. 2017

View full text Add to dashboard Cite

show abstract

Effects of Catheterization on Artery Function and Health: When Should Patients Start Exercising Following Their Coronary Intervention?

2019

Self Cite

View full text Add to dashboard Cite

Coronary artery disease (CAD) is a leading cause of death worldwide, and percutaneous transluminal coronary angiography (PTCA) and/or percutaneous coronary intervention (PCI; angioplasty) are commonly used to diagnose and/or treat the obstructed coronaries. Exercise-based rehabilitation is recommended for all CAD patients; however, most guidelines do not specify when exercise training should commence following PTCA and/or PCI. Catheterization can result in arterial dysfunction and acute injury, and given that fact that exercise, particularly at higher intensities, is associated with elevated inflammatory and oxidative stress, endothelial dysfunction and a pro-thrombotic milieu, performing exercise post-PTCA/PCI may transiently elevate the risk of cardiac events. This review aims to summarize extant literature relating to the impacts of coronary interventions on arterial function, including the time-course of recovery and the potential deleterious and/or beneficial impacts of acute versus long-term exercise. The current literature suggests that arterial dysfunction induced by catheterization recovers 4-12 weeks following catheterization. This review proposes that a period of relative arterial vulnerability may exist and exercise during this period may contribute to elevated event susceptibility. We therefore suggest that CAD patients start an exercise-training program between 2 and 4 weeks post-PCI, recognizing that the literature suggest there is a "grey area" for functional recovery between 2-12 weeks post catheterization. The timing of exercise onset should take into consideration the individual characteristics of patients (age, severity of disease, comorbidities) and the intensity, frequency and duration of the exercise prescription.

show abstract

Impact of handgrip exercise intensity on brachial artery flow-mediated dilation

Cited by 33 publications

References 41 publications

Thirty minutes of handgrip exercise potentiates flow‐mediated dilatation in response to sustained and transient shear stress stimuli to a similar extent

Thirty minutes of handgrip exercise potentiates flow‐mediated dilatation in response to sustained and transient shear stress stimuli to a similar extent

The influence of vitamin C on the interaction between acute mental stress and endothelial function

Effects of Catheterization on Artery Function and Health: When Should Patients Start Exercising Following Their Coronary Intervention?

Contact Info

Product

Resources

About