Impact of Healthcare-Associated Infections on Length of Stay: A Study in 68 Hospitals in China

Abstract

Healthcare-associated infections (HAIs) not only bring additional medical cost to the patients but also prolong the length of stay (LOS). 2119 HAI case-patients and 2119 matched control-patients were identified in 68 hospitals in 14 primary sampling provinces of 7 major regions of China. The HAI caused an increase in stay of 10.4 days. The LOS due to HAI increased from 9.7 to 10.9 days in different levels of hospitals. There was no statistically significant difference in the increased LOS between different hospital levels. The increased LOS due to HAI in different regions was 8.2 to 12.6 days. Comparing between regions, we found that the increased LOS due to HAI in South China is longer than other regions except the Northeast. The gastrointestinal infection (GI) caused the shortest extra LOS of 6.7 days while the BSI caused the longest extra LOS of 12.8 days. The increased LOS for GI was significantly shorter than that of other sites. Among 2119 case-patients, the non-multidrug-resistant pathogens were detected in 365 cases. The average increased LOS due to these bacterial infections was 12.2 days. E. coli infection caused significantly shorter LOS. The studied MDROs, namely, MRSA, VRE, ESBLs-E. coli, ESBLs-KP, CR-E. coli, CR-KP, CR-AB, and CR-PA were detected in 381 cases (18.0%). The average increased LOS due to these MDRO infections was 14 days. Comparing between different MDRO infections, we found that the increased LOS due to HAI caused by CR-PA (26.5 days) is longer than other MDRO infections (shorter than 19.8 days).

High Prevalence of Multidrug-Resistant Bacteria in the Centre Hospitalier et Universitaire de la Mère et de l’Enfant Lagune (CHU-MEL) Reveals Implications of Poor Hygiene Practices in Healthcare

“…Healthcare-associated infections (HAIs) are known worldwide as a public health problem, which have led to a significant increase in mortality, morbidity, and cost of patient care due to longer stays [1]. Their frequency and severity are particularly high in the intensive care settings because of the pathologies presented by the patients, the associated comorbidities, and the density of the invasive techniques used [2,3].…”

Length of Stay in Patients With Central Line-Associated Bloodstream Infection at a Tertiary Hospital in the Kingdom of Saudi Arabia

“…In Jia et al’s recent study, which was undertaken across 68 hospitals, the results suggested that LOS may be influenced by an organism’s sensitivity to antibiotics. For non-drug-resistant organism infections, the LOS was 12.2 days, whereas it was 14 days for multi-drug-resistant organism infections in hospital-acquired bloodstream infections [ 15 ].…”

Impact of Multidisciplinary Collaborative Intervention on Isolation Implementation in the Prevention and Control of Multidrug Resistance Infection—A Retrospective Study

“…On the other hand, MDRO infection will prolong the hospital stays of patients [28]. A study on the impact of hospital infections on the LOS in 68 hospitals in China found that MDRO infection increased the average LOS by one day, and the maximum number of days for CR-PA infection increased by 26 days [29]. Langeveld [30] also found that the MDRO group had an average of 25 more hospital stays than the non-resistant group.…”