Impact of Intragastric Balloon Treatment on Adipokines, Cytokines, and Metabolic Profile in Obese Individuals

Efficacy of Intragastric Balloons in the Markers of Metabolic Dysfunction-associated Fatty Liver Disease: Results from Meta-analyses

“…Figure 1 summarizes the flow diagram of the selection process performed to identify eligible studies in this systematic review. Out of 152 references, a total of 14 studies [25][26][27][28][29][30][31][32][33][34][35][36][37][38] comprising 624 participants met the predefined inclusion criteria. All studies were published prior to September 13, 2020.…”

“…Summary of study characteristics: Eight studies [25][26][27]29,33,35,36,38 with a total of 352 individuals were included in this meta-analysis of HOMA-IR level, and their characteristics are summarized in Table 1. All included studies were published after 2007.…”

“…All included studies were published after 2007. Of these, one 38 was a two-arm RCT, and the rest [25][26][27]29,33,35,36 were observational longitudinal studies, meaning that a total of nine intervention arms were included in this analysis. The participants came from three countries (Brazil, Italy, Japan).…”

“…The participants came from three countries (Brazil, Italy, Japan). Seven intervention arms [25][26][27]29,33,38 applied the Orbera IGB system, one arm 36 used the Orbera/Spatz IGB system, and the single remaining arm 35 reported results with the Elipse IGB system. Furthermore, the range of average baseline HOMA-IR was from 2.36 to 12.30.…”

“…Quantitative synthesis and stratified analyses: Nine intervention arms [25][26][27]29,33,35,36,38 of 352 participants evaluated the effect of IGB on HOMA-IR. The pooled mean decrease in HOMA-IR levels with IGB therapy was 1.56 (95% CI=1.16-1.95, I 2 =61.1; Fig.…”