Impact of multi-electrode renal sympathetic denervation on short-term blood pressure variability in patients with drug-resistant hypertension. Insights from the EnligHTN I study

Tsioufis, Costas; Papademetriou, Vasilios; Tsiachris, Dimitris; Κασιακόγιας, Αλέξανδρος; Kordalis, Athanasios; Thomopoulos, Costas; Dimitriadis, Kyriakos; Tousoulis, Dimitrios; Stefanadis, Christodoulos; Parati, Gianfranco; Worthley, Stephen G.

doi:10.1016/j.ijcard.2014.11.121

Cited by 14 publications

(3 citation statements)

References 23 publications

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“…There were 7 RCTs and 6 controlled studies, and case number ranged from 9 to 341 patients across the studies. Ten studies compared RD with control, [8–13,15–19,21] 2 studies compared RD with adjusted drugs, [14,20] and 1 study compared combined therapy with monotherapy of adjusted drugs. [22] Baseline SBP ranged from 144 to 181 mm Hg and DBP ranged from 81 to 97 mm Hg in RD group.…”

Section: Resultsmentioning

confidence: 99%

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Renal denervation, adjusted drugs, or combined therapy for resistant hypertension

Cheng²,

Li³

et al. 2016

Medicine

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Section: Resultsmentioning

confidence: 99%

“…Two kinds of catheters were reported, and 13 studies adopted a Symplicity Cather System except for 1 study adopted a EnglisHTN. [19] …”

Section: Resultsmentioning

confidence: 99%

Renal denervation, adjusted drugs, or combined therapy for resistant hypertension

Cheng²,

Li³

et al. 2016

Medicine

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“…In this regard a recent meta-analysis showed that RDN in resistant hypertensive patients favourably affects short-term BPV, independently of the BP level reduction [176]. RDN also reduced the 24-h BP time rate [177]. Further investigation on whether RDN-induced reductions in BPV are translated in improved cardiovascular protection, is needed.…”

Section: Clinical Relevance Of Blood Pressure Variabilitymentioning

confidence: 99%

Blood pressure variability: methodological aspects, clinical relevance and practical indications for management - a European Society of Hypertension position paper ∗

Parati

Bilo

Pengo

et al. 2023

Journal of Hypertension

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Blood pressure is not a static parameter, but rather undergoes continuous fluctuations over time, as a result of the interaction between environmental and behavioural factors on one side and intrinsic cardiovascular regulatory mechanisms on the other side. Increased blood pressure variability (BPV) may indicate an impaired cardiovascular regulation and may represent a cardiovascular risk factor itself, having been associated with increased all-cause and cardiovascular mortality, stroke, coronary artery disease, heart failure, end-stage renal disease, and dementia incidence. Nonetheless, BPV was considered only a research issue in previous hypertension management guidelines, because the available evidence on its clinical relevance presents several gaps and is based on heterogeneous studies with limited standardization of methods for BPV assessment. The aim of this position paper, with contributions from members of the European Society of Hypertension Working Group on Blood Pressure Monitoring and Cardiovascular Variability and from a number of international experts, is to summarize the available

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MRI-based detection of renal artery abnormalities related to renal denervation by catheter-based radiofrequency ablation in drug resistant hypertensive patients

et al. 2018

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Impact of multi-electrode renal sympathetic denervation on short-term blood pressure variability in patients with drug-resistant hypertension. Insights from the EnligHTN I study

Cited by 14 publications

References 23 publications

Renal denervation, adjusted drugs, or combined therapy for resistant hypertension

Renal denervation, adjusted drugs, or combined therapy for resistant hypertension

Blood pressure variability: methodological aspects, clinical relevance and practical indications for management - a European Society of Hypertension position paper ∗

MRI-based detection of renal artery abnormalities related to renal denervation by catheter-based radiofrequency ablation in drug resistant hypertensive patients

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