Impact of Nanolayered Material and Nanohybrid Modifications on Their Potential Antibacterial Activity

Abstract

Due to an escalating increase in multiple antibiotic resistance among bacteria, novel nanomaterials with antimicrobial properties are being developed to prevent infectious diseases caused by bacteria that are common in wastewater and the environment. A series of nanolayered structures and nanohybrids were prepared and modified by several methods including an ultrasonic technique, intercalation reactions of fatty acids, and carbon nanotubes, in addition to creating new phases based on zinc and aluminum. The nanomaterials prepared were used against a group of microorganisms, including E. coli, S. aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa. Experimental results revealed that a nanohybrid based on carbon nanotubes and fatty acids showed significant antimicrobial activity against E. coli, and can be implemented in wastewater treatment. Similar behavior was observed for a nanolayered structure which was prepared using ultrasonic waves. For the other microorganisms, a nanolayered structure combined with carbon nanotubes showed a significant and clear inhibitory effect on S. aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa. It is concluded that the nanolayered structures and nanohybrids, which can be modified at low cost with high productivity, using simple operations and straightforward to use equipment, can be considered good candidates for preventing infectious disease and inhibiting the spread of bacteria, especially those that are commonly found in wastewater and the environment.

Efficient Dye Degradation and Antimicrobial Behavior with Molecular Docking Performance of Silver and Polyvinylpyrrolidone-Doped Zn-Fe Layered Double Hydroxide

“…The in vitro antibacterial activity of surface-modified Zn−Fe LDH hybrid with intercalated nitrate anions displayed antimicrobial effects against E. coli, suggesting their possible use in sewage wastewater bioremediation. 63,64 A literature comparison of the antibacterial activity of the synthesized nanocomposites with that of the present study is illustrated in Table S2.…”

Biosynthesis, Characterization, and Antifungal Activity of Novel Trimetallic Copper Oxide–Selenium–Zinc Oxide Nanoparticles against Some Mucorales Fungi

“…Unfortunately, the antibacterial actions of a single nanometal do not affect all of the different types of germs, particularly those microbes that have developed resistance to the antimicrobial drugs. The requirement for new generations of antimicrobial agents that are relevant to microbial resistance can be supported by utilizing di- or trinanometal structures that are multifunctional and have multiple features that impact the microbial population [ 39 ]. Trimetallic nanoparticles are mainly formed by the combination of three different metals.…”