Impact of Olfactory Impairment on Quality of Life and Disability

Miwa, Takaki; Furukawa, Mitsuru; Tsukatani, Toshiaki; Costanzo, Richard M.; DiNardo, Laurence J.; Reiter, Evan R.

doi:10.1001/archotol.127.5.497

Cited by 429 publications

(387 citation statements)

References 15 publications

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“…Although the total laryngectomized patients' quality of life tends to be worst in relation to the population in general 24,34 , some studies, in accordance to this research, do not show low scores on the quality of life assessment, compared to the population of not laryngectomized subjects.…”

Section: Discussionsupporting

confidence: 73%

Acuidade olfatória e qualidade de vida após a laringectomia total

et al. 2015

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RESUMO: Objetivo: identificar a prevalência e os fatores associados às alterações do olfato e descrever a qualidade de vida após a laringectomia total. Métodos: estudo transversal para avaliar a acuidade olfatória e a qualidade de vida de laringectomizados totais no Instituto Nacional de Câncer por meio da aplicação do Teste de Identificação do Olfato da Universidade da Pensilvânia, do Questionário de Qualidade de Vida da Universidade de Washington e do Questionário sobre a Acuidade Olfatória Pré-Reabilitação do Olfato. Resultados: foram avaliados 48 laringectomizados totais, sendo 39 do sexo masculino e 9 do sexo feminino, com idade média de 62 anos e tempo médio de 5,6 anos desde a laringectomia total. No Teste de Identificação do Olfato a pontuação média foi de 17,9. De acordo com a classificação do olfato no teste, a maioria dos participantes apresentou algum grau de alteração, sendo que apenas 2 indivíduos tiveram o olfato considerado dentro da normalidade. No Questionário de Qualidade de vida da Universidade de Washington, o escore composto foi 80,47. Os domínios que apresentaram as médias de pontos mais baixas foram paladar, saliva e fala. No questionário sobre a acuidade olfatória pré-reabilitação do olfato, a maioria dos participantes consideraram seu olfato de ruim a razoável. 21 indivíduos relataram apresentar algum grau de dificuldade em suas atividades de vida diária em decorrência de alterações do olfato. Conclusão: os laringectomizados totais apresentaram alta prevalência de alterações do olfato, com comprometimentos relacionados às suas atividades de vida diária.

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Section: Discussionsupporting

confidence: 73%

Acuidade olfatória e qualidade de vida após a laringectomia total

et al. 2015

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“…Lower quality of life is not the only result of olfactory impairment. Miwa et al 31 showed an increased occurrence of disability in this group of patients. In another study, 32 impaired olfaction was a risk factor for certain injuries because normosmia allows early detection and avoidance of potentially hazardous situations, such as cooking or house fires, delayed detection of gas leaks, and exposure to or ingestion of toxic substances.…”

Section: Methodsmentioning

confidence: 65%

Association of olfactory function with the intensity of self-reported physical activity in adults with type 1 diabetes

Falkowski¹,

Chudzinski²,

Jakubowska³

et al. 2017

Polish Archives of Internal Medicine

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“…23 Patients frequently do not discuss their olfaction difficulties; however, the loss of smell can lead to depression and a lower quality of life. [26][27][28][29] Loss of smell can also lead to safety issues and severely altered eating habits and nutritional intake. 30 Resolution of anosmia is unlikely in most cases because the majority of patients with olfaction problems receive from their physician no, unclear, or unsatisfactory information about their diagnosis and prognosis.…”

Section: Discussionmentioning

confidence: 99%

A possible correlation between vitamin D deficiency and loss of smell: 2 case reports

Kruse¹,

Cambron

2011

Journal of Chiropractic Medicine

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Objective: The purpose of this report is to present 2 cases of diminished olfaction that improved with increasing serum levels of vitamin D3. Clinical Features: Both patients were under the care of medical and chiropractic physicians for various complaints. A 47-year-old hyposmic woman was diagnosed with vitamin D deficiency who incidentally noticed a progressive return of her sense of smell while taking vitamin D supplements as prescribed by her medical doctor. A 34-year-old anosmic woman noticed a direct relationship with her ability to smell and vitamin D3 supplementation. Intervention and Outcome: Treatment for the first patient consisted of vitamin D supplementation of 10 000 IU a day. Her serum D3 levels increased substantially over a period of 8 months, at which time she reported a marked improvement in her sense of smell. The second patient was prescribed 50 000 IU of vitamin D a week; and she reported an increased ability to smell, although only the strongest of odors. Conclusion: A link between hypovitaminosis D and a diminished sense of smell was noted in these 2 individuals.

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Impact of Olfactory Impairment on Quality of Life and Disability

Abstract: Patients reporting persistent olfactory impairment after previously documented olfactory loss indicate a higher level of disability and lower quality of life than those with perceived resolution of olfactory compromise.

Cited by 429 publications

References 15 publications

Acuidade olfatória e qualidade de vida após a laringectomia total

Acuidade olfatória e qualidade de vida após a laringectomia total

Association of olfactory function with the intensity of self-reported physical activity in adults with type 1 diabetes

A possible correlation between vitamin D deficiency and loss of smell: 2 case reports

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