Impact of paper filtered coffee on oxidative DNA-damage: Results of a clinical trial

Mišík, Miroslav; Hoelzl, Christine; Wagner, Karl‐Heinz; Cavin, Christophe; Moser, Berthold; Kundi, Michael; Simić, Tatjana; Elbling, Leonilla; Kager, Nina; Ferk, Franziska; Ehrlich, Veronika; Nersesyan, Armen; Dušinská, Maria; Schilter, Benoı̂t; Knasmüller, Siegfried

doi:10.1016/j.mrfmmm.2010.08.003

Cited by 66 publications

(43 citation statements)

References 50 publications

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“…It may also protect against low-density lipoprotein oxidation and reduce oxidative DNA damage. 23 Caffeine is also an A 2A adenosine receptor antagonist, and selective A 2A -antagonists have been shown to be neuroprotective and attenuate dopamine loss. 24 In animal models of PD, treatment with caffeine ameliorated oxidative stress, restored the depletion of midbrain and striatal dopamine, prevented decline in motor activities and muscular strength, and improved norepinephrine level.…”

Section: Discussionmentioning

confidence: 99%

The association between lifestyle factors and Parkinson's disease progression and mortality

et al. 2019

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Background: Lifestyle factors may contribute to the development of Parkinson’s disease, but little is known about factors that influence progression. The objective of the current study was to examine whether caffeine or alcohol consumption, physical activity, or cigarette smoking is associated with progression and survival among PD patients. Methods: We assessed lifelong coffee, tea, and alcohol consumption, smoking, and physical activity in a prospective community-based cohort (n = 360). All patients were passively followed for mortality (2001–2016); 244 were actively followed on average ± SD 5.3 ± 2.1 years (2007–2014). Movement disorder specialists repeatedly assessed motor function (Hoehn & Yahr) and cognition (Mini-Mental State Exam). We used Cox proportional hazards models and inverse probability weights to account for censoring. Results: Coffee, caffeinated tea, moderate alcohol consumption, and physical activity were protective against at least 1 outcome. Smoking and heavy alcohol consumption were associated with increased risks. Coffee was protective against time to Hoehn & Yahr stage 3 (hazard ratio, 0.52; 95% confidence interval, 0.28–1.01), cognitive decline (hazard ratio, 0.23; 95% confidence interval, 0.11,0.48), and mortality (hazard ratio, 0.47; 95% confidence interval, 0.32–0.69). Relative to moderate drinkers, those who never drank liquor and those who drank more heavily were at an increased risk of Hoehn & Yahr 3 (hazard ratio, 3.48; 95% confidence interval, 1.90–6.38; and hazard ratio, 2.16; 95% confidence interval, 1.03, 4.54, respectively). A history of competitive sports was protective against cognitive decline (hazard ratio, 0.46; 95% confidence interval, 0.22–0.96) and Hoehn & Yahr 3 (hazard ratio, 0.42; 95% confidence interval, 0.23–0.79), as was physical activity measured by metabolic-equivalent hours. Current cigarette smoking was associated with faster cognitive decline (hazard ratio, 3.20; 95% confidence interval, 1.02–10.01). Conclusions: This population-based study suggests that lifestyle factors influence PD progression and mortality.

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Section: Discussionmentioning

confidence: 99%

The association between lifestyle factors and Parkinson's disease progression and mortality

et al. 2019

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“…38,39 Keratinocytes exposed to UV light have DNA damage, and the erythema reaction is triggered by the production and release of cytokines and chemical mediators that stimulate dermal vessels. 44 Ferulic acid, a major phenolic component, appears in the circulation after the consumption of coffee 45 and eliminated c-ray-induced DNA damage in rats. 40,41 It is unknown how coffee can reduce hyperpigmentation.…”

Section: Discussionmentioning

confidence: 99%

Skin photoprotection and consumption of coffee and polyphenols in healthy middle‐aged Japanese females

Fukushima¹,

Takahashi

Hori

et al. 2014

Int J Dermatology

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“…This is not surprising, since according to the production process of instant coffee, which involves extraction and concentration of water-soluble or dispersible compounds (including polyphenols), instant coffee contains higher content of these substances when compared to other types of coffee. Mišik et al (2010) studied the effect of paper-filtered coffee on oxidative DNA damage and found that filtration of coffee brews led to removal of some bioactive compounds. Lower total phenol and total flavonoid contents of filter coffee could be due to the filter used during the brew preparation.…”

Section: Effects Of Preparation Techniques On the Content Of Polyphenmentioning

confidence: 99%

Effects of Preparation Techniques on the Antioxidant Capacity of Coffee Brews

Komes¹,

Belščak‐Cvitanović²

2014

Processing and Impact on Antioxidants in Beverages

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Impact of paper filtered coffee on oxidative DNA-damage: Results of a clinical trial

Cited by 66 publications

References 50 publications

The association between lifestyle factors and Parkinson's disease progression and mortality

The association between lifestyle factors and Parkinson's disease progression and mortality

Skin photoprotection and consumption of coffee and polyphenols in healthy middle‐aged Japanese females

Effects of Preparation Techniques on the Antioxidant Capacity of Coffee Brews

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