Impact of pharmacist intervention on antibiotic use and prophylactic antibiotic use in urology clean operations

Zhou, Ying; Ma, L.-Y.; Zhao, Xiuli; Tian, Shuohan; Sun, Li‐Ying; Chen, Yimin

doi:10.1111/jcpt.12275

Cited by 47 publications

(50 citation statements)

References 7 publications

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“…3 Same protocol for acute uncomplicated pyelonephritis and complicated urinary tract infection (stratification not always possible). 4 Not investigated as sole substance in acute uncomplicated pyelonephritis. 5 Principally for gram-positive pathogens.…”

Section: Prevention Of Recurrent Urinary Tract Infection: Standard Groupmentioning

confidence: 99%

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The 2017 Update of the German Clinical Guideline on Epidemiology, Diagnostics, Therapy, Prevention, and Management of Uncomplicated Urinary Tract Infections in Adult Patients. Part II: Therapy and Prevention

et al. 2018

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Background: We aimed to update the 2010 evidence- and consensus-based national clinical guideline on the diagnosis and management of uncomplicated urinary tract infections (UTIs) in adult patients. Results are published in 2 parts. Part 1 covers methods, the definition of patient groups, and diagnostics. This second publication focuses on treatment of acute episodes of cystitis and pyelonephritis as well as on prophylaxis of recurrent UTIs. Materials and Methods: An interdisciplinary group consisting of 17 representatives of 12 medical societies and a patient representative was formed. Systematic literature searches were conducted in MEDLINE, EMBASE, and the Cochrane Library to identify literature published in 2010–2015. Results: For the treatment of acute uncomplicated cystitis (AUC), fosfomycin-trometamol, nitrofurantoin, nitroxoline, pivmecillinam, and trimethoprim (depending on the local rate of resistance) are all equally recommended. Cotrimoxazole, fluoroquinolones, and cephalosporins are not recommended as antibiotics of first choice, for concern of an unfavorable impact on the microbiome. Mild to moderate uncomplicated pyelonephritis should be treated with oral cefpodoxime, ceftibuten, ciprofloxacin, or levofloxacin. For AUC with mild to moderate symptoms, instead of antibiotics symptomatic treatment alone may be considered depending on patient preference after discussing adverse events and outcomes. Primarily non-antibiotic options are recommended for prophylaxis of recurrent urinary tract infection. Conclusion: In accordance with the global antibiotic stewardship initiative and considering new insights in scientific research, we updated our German clinical UTI guideline to promote a responsible antibiotic use and to give clear hands-on recommendations for the diagnosis and management of UTIs in adults in Germany for healthcare providers and patients.

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Section: Prevention Of Recurrent Urinary Tract Infection: Standard Groupmentioning

confidence: 99%

“…Antibiotic resistance is a growing global problem that leads to significant challenges and costs in the health care system [1][2][3][4]. We updated the German clinical UTI guideline to promote a responsible antibiotic use in the management of UTIs in adults in Germany.…”

Section: Introductionmentioning

confidence: 99%

The 2017 Update of the German Clinical Guideline on Epidemiology, Diagnostics, Therapy, Prevention, and Management of Uncomplicated Urinary Tract Infections in Adult Patients. Part II: Therapy and Prevention

et al. 2018

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“…In terms of the existing health insurance and the total expense control system in Beijing medical institutions, this difference is equivalent to a savings of more than 4 million Yuan for the health insurance fund. [5] The average antibiotic cost of urology operations, for instance, decreased from 2077.49 to 559.67 Yuan between 2013 and 2010, with a 27.7% decrease in antibiotic cost, while the rate of bacterial infection in surgery did not increase. [5]…”

Section: Effects Of Clinical Pharmacy Servicesmentioning

confidence: 99%

“…[5] The average antibiotic cost of urology operations, for instance, decreased from 2077.49 to 559.67 Yuan between 2013 and 2010, with a 27.7% decrease in antibiotic cost, while the rate of bacterial infection in surgery did not increase. [5]…”

Section: Effects Of Clinical Pharmacy Servicesmentioning

confidence: 99%

Peking University Health Science Center Model of Clinical Pharmacy Education and Clinical Pharmacist Services

Chen

Zhou

et al. 2016

Chinese Medical Journal

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“…Antibiotic resistance is a growing global problem that leads to significant challenges and costs in the health care system [1][2][3][4][5]. The resistance level of pathogens against commonly used antibiotics of uncomplicated UTIs has significantly increased in recent years.…”

Section: Introductionmentioning

confidence: 99%

The 2017 Update of the German Clinical Guideline on Epidemiology, Diagnostics, Therapy, Prevention, and Management of Uncomplicated Urinary Tract Infections in Adult Patients: Part 1

et al. 2018

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Objectives: We aimed to update the 2010 evidence-and consensus-based national clinical guideline on the diagnosis and management of uncomplicated urinary tract infections (UTIs) in adult patients. Materials and Methods: An interdisciplinary group consisting of 17 representatives of 12 medical societies and a patient representative was formed. Systematic literature searches were conducted in MEDLINE, EMBASE, and the Cochrane Library to identify literature published in 2010-2015. Results: We provide 75 recommendations and 68 statements in the updated evidence-and consensus-based national clinical guideline. The diagnostics part covers practical recommendations on cystitis and pyelonephritis for each defined patient group. Clinical examinations, as well as laboratory testing and microbiological pathogen assessment, are addressed. Conclusion: In accordance with the global antibiotic stewardship initiative and considering new insights in scientific research, we updated our German clinical UTI guideline to promote a responsible antibiotic use and to give clear hands-on recommendations for the diagnosis and management of UTIs in adults in Germany for healthcare providers and patients.

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Impact of pharmacist intervention on antibiotic use and prophylactic antibiotic use in urology clean operations

Abstract: The study illustrates how an antibiotic stewardship programme with pharmacist participation including real-time interventions can promote improved antibiotic-prescribing and significantly decrease costs.

Cited by 47 publications

References 7 publications

The 2017 Update of the German Clinical Guideline on Epidemiology, Diagnostics, Therapy, Prevention, and Management of Uncomplicated Urinary Tract Infections in Adult Patients. Part II: Therapy and Prevention

The 2017 Update of the German Clinical Guideline on Epidemiology, Diagnostics, Therapy, Prevention, and Management of Uncomplicated Urinary Tract Infections in Adult Patients. Part II: Therapy and Prevention

Peking University Health Science Center Model of Clinical Pharmacy Education and Clinical Pharmacist Services

The 2017 Update of the German Clinical Guideline on Epidemiology, Diagnostics, Therapy, Prevention, and Management of Uncomplicated Urinary Tract Infections in Adult Patients: Part 1

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