Impact of physical exercise on visceral adipose tissue fatty acid profile and inflammation in response to a high-fat diet regimen

Effects of short-term Pilates exercise on selected blood parameters

“…Our finding that there was already a reduction in MCP-1 after 2 weeks of Pilates exercise complements the findings of others who reported that, in long term physical activity regimes, total levels of biomarkers of inflammation improved (Lunde et al 2017). Similarly, endurance training (ET) reduced inflammatory markers (TNF-α, IL-6), macrophage recruitment (MCP-1 and F4/80) and increased the IL-10/TNF-α ratio in plasma (Rocha-Rodrigues et al 2017). MCP-1 and TNF-α also decreased in the group of healthy men who performed aerobic and resistance training on alternating days (AD) 4-6 d/wk (Ihalainen et al 2018).…”

Capsaicinoids improve consequences of physical activity

“…Regular exercise is known for enhancing the levels of anti-inflammatory and antioxidant markers such as NF-κB, IL-10, tumor necrosis factor-α (TNF-α) and Nrf2 [ 12 , 19 , 42 ]. The NF-κB pathway plays an important role in the induction of oxidative stress.…”

“…This study demonstrates that regular exercise and CAPs affected the ability of oxidative stress to activate NF-κB (p65), indicating that they play a key role in inhibition of the NF-κB pathway, which translocates the latent transcription factor to the nucleus. These markers are indicators for inflammation and related diseases and by increasing Nrf2 pathway and AMPK, a metabolic sensor and a key enzyme in muscle metabolism levels [ 8 , 42 , 43 ]. Tang et al [ 44 ] reported that capsaicin inhibits lipopolysaccharide (LPS)-stimulated IL-1β, IL-6, TNF-α and NF-κB production in a time- and dose-dependent manner.…”

International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2Receptors (EP1–4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions

“…Recently, we and other groups have demonstrated that PGE 2 levels in plasma and omental adipose tissue are greater in obese patients (García-Alonso et al, 2016;Ozen et al, 2019), whereas there are conflicting results in terms of the PGE 2 levels measured in obese rodent models (Pham Huu Chanh et al, 1987;Cunha et al, 2010;Rocha-Rodrigues et al, 2017). Another difference has been in the detected level of mPGES-1 expression between obese patients and obese rodents: mPGES-1 expression remained unchanged in the adipose tissue of obese patients, whereas it is decreased in those obtained for obese mice (Hétu and Riendeau, 2007;García-Alonso et al, 2016).…”