Impact of physician assistance on the reliability of the International Index of Erectile Function

Bayraktar, Zeki; Atun, Ihsan

doi:10.1111/j.1439-0272.2012.01312.x

Cited by 3 publications

(9 citation statements)

References 15 publications

(29 reference statements)

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“…Questionnaires are the main tools to evaluate erectile function in humans. Among these questionnaires, the IIEF is the most widely used multidimensional self‐report instrument (Rosen et al ., ; Bayraktar & Atun, ). Despite strong psychometric properties and wide adoption, the IIEF has limitations or weaknesses in specific areas.…”

Section: Discussionmentioning

confidence: 99%

Changes in erectile organ structure and function in a rat model of chronic prostatitis/chronic pelvic pain syndrome

et al. 2015

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There is a growing recognition of the association between chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and erectile dysfunction (ED); however, most of the reports are based on questionnaires which cannot distinguish between organic and functional ED. The purpose of this study was to determine the exact relationship between CP/CPPS and ED, and to investigate the changes in erectile organ structure and function in a rat model of CP/CPPS. We established a rat model of experimental autoimmune prostatitis (EAP), which is a valid model for CP/CPPS. Erectile function in EAP and normal rats was comparable after cavernous nerve electrostimulation. The serum testosterone and oestradiol levels, ultrastructure of the corpus cavernosum and expression of endothelial nitric oxide synthase and neuronal nitric oxide synthase in the two groups were similar; however, there was a decrease in smooth muscle-to-collagen ratio and alpha-smooth muscle actin expression and an increase in transforming growth factor-beta 1 expression was observed in EAP rats. Thus, organic ED may not exist in EAP rats. We speculate that ED complained by patients with CP/CPPS may be psychological, which could be caused by impairment in the quality of life; however, further studies are needed to fully understand the potential mechanisms underlying the penile fibrosis in EAP rats.

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Section: Discussionmentioning

confidence: 99%

Changes in erectile organ structure and function in a rat model of chronic prostatitis/chronic pelvic pain syndrome

et al. 2015

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“…15 studies reported on internal consistency of the IIEF-15 1,15,16,22,26,28,31,34e36,38,41,43,50,51 (Supplementary Table 1). Methodologic quality of these studies was rated as "very good", 1,16,22,28,36,38,50,51 "adequate", 26,31,43 or "inadequate". 16,34,35,41 The inadequate scores were due to only reporting internal consistency for the total IIEF-15 instead of its subscales 16,34,41 or because of a very small sample size ("other flaws" in COSMIN methodologic quality).…”

Section: Internal Consistencymentioning

confidence: 99%

“…Methodologic quality of these studies was rated as "very good", 1,16,22,28,36,38,50,51 "adequate", 26,31,43 or "inadequate". 16,34,35,41 The inadequate scores were due to only reporting internal consistency for the total IIEF-15 instead of its subscales 16,34,41 or because of a very small sample size ("other flaws" in COSMIN methodologic quality). 35 8 studies, of "very good", 15,28,36,50 "adequate", 31 and "inadequate" 34,35,41 quality, reported Cronbach's a of sufficient values of the IIEF-15.…”

Section: Internal Consistencymentioning

confidence: 99%

“…5 studies, of "very good" 1,22,38,51 and "adequate" 26 quality, reported Cronbach's a of insufficient values of the IIEF-15. In 2 studies, the evidence on internal consistency was rated as indeterminate because it could not be interpreted: 1 study did not report the internal consistency per subscale, 16 and 1 study reported internal consistency for 2 subscales, resulting from their PCA results. 43 5 studies reported on internal consistency of the IIEF-5 47e51 (Supplementary Table 1).…”

Section: Internal Consistencymentioning

confidence: 99%

“…8 studies reported on test-retest reliability of the IIEF-15 1,15,16,35,36,40,51 (Table 3). Methodologic quality of these studies was rated as "doubtful", 1,16,26,36,40,51 or "inadequate".…”

Section: Test-retest Reliabilitymentioning

confidence: 99%

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The International Index of Erectile Function (IIEF)—A Systematic Review of Measurement Properties

Neijenhuijs

Holtmaat

Aaronson

et al. 2019

The Journal of Sexual Medicine

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Introduction: The International Index of Erectile Function (IIEF) is a patient-reported outcome measure to evaluate erectile dysfunction and other sexual problems in men. Aim: To perform a systematic review of the measurement properties of the 15-item patient-reported outcome measure (IIEF-15) and the shortened 5-item version (IIEF-5). Methods: A systematic search of scientific literature up to April 2018 was performed. Data were extracted and analyzed according to COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) guidelines for structural validity, internal consistency, reliability, measurement error, hypothesis testing for construct validity, and responsiveness. Evidence of measurement properties was categorized into sufficient, insufficient, inconsistent, or indeterminate, and quality of evidence as very high, high, moderate, or low. Results: 40 studies were included. The evidence for criterion validity (of the Erectile Function subscale), and responsiveness of the IIEF-15 was sufficient (high quality), but inconsistent (moderate quality) for structural validity, internal consistency, construct validity, and test-retest reliability. Evidence for structural validity, testretest reliability, construct validity, and criterion validity of the IIEF-5 was sufficient (moderate quality) but indeterminate for internal consistency, measurement error, and responsiveness. Clinical Implications: Lack of evidence for and evidence not supporting some of the measurement properties of the IIEF-15 and IIEF-5 shows the importance of further research on the validity of these questionnaires in clinical research and clinical practice. Strengths & Limitations: A strength of the current review is the use of predefined guidelines (COSMIN). A limitation of this review is the use of a precise rather than a sensitive search filter regarding measurement properties to identify studies to be included. Conclusion: The IIEF requires more research on structural validity (IIEF-15), internal consistency (IIEF-15 and IIEF-5), construct validity (IIEF-15), measurement error (IIEF-15 and IIEF-5), and responsiveness (IIEF-5). The most pressing matter for future research is determining the unidimensionality of the IIEF-5 and the exact factor structure of the IIEF-15. Neijenhuijs KI, Holtmaat K, Aaronson NK, et al. The International Index of Erectile Function (IIEF)-A Systematic Review of Measurement Properties. J Sex Med 2019;16:1078e1091.

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Evaluation of sexual functional status and consistency of scales in patients with hypogonadotropic hypogonadism before and after testosterone replacement therapy: a single-center experience

Aydoğan

Doğaner

Haymana

et al. 2022

Archives of Endocrinology and Metabolism

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Objective: This study aimed to investigate the frequency of sexual dysfunction and the effect of shortterm testosterone replacement therapy on sexual functions in congenital hypogonadism patients. Furthermore, we sought to reveal the consistency of the self-report scales used for the diagnosis of sexual dysfunction and the relationship between biochemical parameters. Materials and methods:The study was conducted on 47 young male patients aged above 18 years who were diagnosed with hypogonadotropic hypogonadism. Short (IIEF-5) and long (IIEF-15) forms of the International Index of Erectile Function and Arizona Sexual Experiences Scale (ASEX) were applied before treatment under the supervision of a physician. The patients' blood pressure, height, and weight were measured, and their luteinizing hormone (LH), FSH, and total testosterone levels were recorded. Patients who started their treatments were called for a follow-up checkup after 6 months. Their blood pressure, height, and weight were measured by reapplying the ASEX, IIEF-5, and IIEF-15. In addition, their LH, FSH, and total testosterone levels in the biochemical tests were rerecorded. Results: In this study, the sexual dysfunction status of patients diagnosed with hypogonadotropic hypogonadism before and after treatment was evaluated using the ASEX, IIEF-15, and IIEF-5 scales. A decrease in sexual dysfunction was observed in all three scales after treatment compared with that before treatment. The IIEF-5 and IIEF-15 scales were found to be uncorrelated in terms of the pretreatment values but were correlated in terms of the post-treatment values. Although a correlation was observed between ASEX and IIEF-5 before treatment, no correlation was detected between ASEX and IIEF-15. After the treatment, ASEX was found to be correlated with both IIEF-5 and IIEF-15. The results of the scales indicated the correlation in all categories, except the pretreatment results of the IIEF-15 scale. Conclusion:The results of the current study demonstrated a significant improvement in the sexual function of hypogonadism patients undergoing short-term testosterone therapy. The ASEX, IIEF-5, and IIEF-15 scales used in the diagnosis and follow-up of sexual dysfunction were useful for evaluating sexual functions in hypogonadotropic hypogonadism patients.

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Impact of physician assistance on the reliability of the International Index of Erectile Function

Cited by 3 publications

References 15 publications

Changes in erectile organ structure and function in a rat model of chronic prostatitis/chronic pelvic pain syndrome

Changes in erectile organ structure and function in a rat model of chronic prostatitis/chronic pelvic pain syndrome

The International Index of Erectile Function (IIEF)—A Systematic Review of Measurement Properties

Evaluation of sexual functional status and consistency of scales in patients with hypogonadotropic hypogonadism before and after testosterone replacement therapy: a single-center experience

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