Impact of prolonged implantable cardioverter-defibrillator arrhythmia detection times on outcomes: A meta-analysis

Scott, Paul A.; Silberbauer, John; McDonagh, Theresa A.; Murgatroyd, Francis

doi:10.1016/j.hrthm.2014.02.009

Cited by 48 publications

(31 citation statements)

References 21 publications

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“…SCD was appropriately prevented by ICDs in inducible patients indicating a relatively high positive predictive value, although not all episodes interrupted by ICDs would necessarily result in SCD [4]. It is probable that the use of longer VT/VF detection intervals might have decreased the ICD activation rate [5]. However, we cannot ignore the non- insignificant incidence of electrical storm in our population, a condition characterized by an extremely unstable arrhythmia substrate carrying an adverse prognosis [6].…”

mentioning

confidence: 93%

Prognostic value of programmed ventricular stimulation for sudden death in selected high risk patients with structural heart disease and preserved systolic function

Gatzoulis¹,

Tsiachris²,

Αρσένος³

et al. 2014

International Journal of Cardiology

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mentioning

confidence: 93%

Prognostic value of programmed ventricular stimulation for sudden death in selected high risk patients with structural heart disease and preserved systolic function

Gatzoulis¹,

Tsiachris²,

Αρσένος³

et al. 2014

International Journal of Cardiology

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“…One important reason might be attributed to the temporal trend of a less aggressive programming of the VT/VF zones. Several studies showed that change of ICD programming to less aggressive therapy resulted in lower mortality rates . Consequently, programming of ICD was adapted during the past 15 years according to the recommendations of the randomized trials.…”

Section: Discussionmentioning

confidence: 99%

Contemporary benefit‐harm profile over two decades in primary prophylactic ICD‐therapy

Kleemann

Strauss

Kouraki

et al. 2019

Clinical Cardiology

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Background Implantable cardioverter defibrillator (ICD) was implemented into clinical routine more than 20 years ago. Since then, ICD therapy became standard therapy for primary and secondary prevention of sudden cardiac death in clinical practice. Objectives Aim of the study was to evaluate the benefit‐harm profile of contemporary primary prophylactic ICD therapy. Methods A total of 1222 consecutive patients of a prospective single‐center ICD‐registry were analyzed who underwent primary prophylactic ICD implantation between 2000 and 2017. Patients were divided into two groups according to the implantation year: 2010‐2017 (group 1, n = 579) and 2000‐2009 (group 2, n = 643). Results The rate of estimated appropriate ICD therapy after 8 years was 51% in the 2000s and 42% in the 2010s (P < .001). The complication rate changed slightly from 53% to 47% (P = .005). This decline was mainly driven by the reduction of inappropriate ICD shocks (30% vs 14%, P < .001) whereas the rate of ICD shock lead malfunction and device/ lead infection remained unchanged over time. Nonischemic cardiomyopathy was an independent predictor for ICD complications without benefit of ICD therapy (HR 1.37, 95% CI 1.07‐1.77). Conclusion The ICD therapy rate for ventricular arrhythmias in patients with primary prophylactic ICD implantation is decreasing over the last two decades. Complication rate remains high due to an unchanged rate of ICD shock malfunctions and device infections. Nonischemic cardiomyopathy is an independent predictor for ICD complications without benefit of ICD therapy in primary prophylactic ICD‐therapy.

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“…These practices have been further solidified in two meta-analyses, which found lenient programming practices were associated with a reduction in mortality and IS rates without an increase in syncope. 68,69 It is clear that in these populations, adopting lenient programming strategies is a safe and effective way to reduce shocks.…”

Section: Device-based Interventions-data From Studies In Adult Patientsmentioning

confidence: 99%

Inappropriate ICD Shocks in Pediatric and Congenital Heart Disease Patients

Garnreiter

2017

J Innov Cardiac Rhythm Manage

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ABSTRACT. Although implantable cardioverter-defibrillators (ICDs) have proven to be life-saving devices, there are frequent complications associated with their use, especially in the pediatric and congenital heart disease populations. Inappropriate shocks are a particularly frequent complication in these groups. This review discusses the causes and implications of inappropriate ICD shocks, and presents potential interventions that may assist in safely reducing the rates of inappropriate shocks in pediatric and congenital heart disease patients with ICDs.

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Impact of prolonged implantable cardioverter-defibrillator arrhythmia detection times on outcomes: A meta-analysis

Cited by 48 publications

References 21 publications

Prognostic value of programmed ventricular stimulation for sudden death in selected high risk patients with structural heart disease and preserved systolic function

Prognostic value of programmed ventricular stimulation for sudden death in selected high risk patients with structural heart disease and preserved systolic function

Contemporary benefit‐harm profile over two decades in primary prophylactic ICD‐therapy

Inappropriate ICD Shocks in Pediatric and Congenital Heart Disease Patients

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