Abstract-In this paper, the interaction of a planar inverted-F antennas array, mounted on a mobile handset, with a human hand-head phantom is investigated in the 1.9 GHz band. The hybrid approach involving the particle swarm optimization (PSO) and Nelder-Mead (NM) algorithm is considered to optimize the complex excitations of the adaptive array elements in a mutual coupling environment for different beamforming synthesis. Firstly, the effect of the human handhead on the handset radiation characteristics is studied. Then, the spatial-peak specific absorption rate (SAR) values of 2-and 4-element PIFA arrays for mobile handset in the vicinity of a human handhead are evaluated numerically for different scenarios. The antenna is analyzed completely using finite difference time domain (FDTD) method while the interaction is performed using the CST Microwave Studio software.