Impact of surface modification on the toxicity of zerovalent iron nanoparticles in aquatic and terrestrial organisms

Yoon, Hakwon; Pangging, Monmi; Jang, Min-Hee; Hwang, Yu Sik; Chang, Yoon Seok

doi:10.1016/j.ecoenv.2018.07.099

Cited by 43 publications

(16 citation statements)

References 38 publications

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“…Despite several changes in the cell death cycle induced by ionic forms of iron, no significant negative effects of nZVI NPs were observed in either type of amoebocytes at environmentally relevant concentrations. The absence of lethal effects is in accordance with in vivo studies focused on the toxicity of nZVI-based material in earthworms and other terrestrial organisms [13,14].…”

Section: Viability Apoptosis and Necrosissupporting

confidence: 83%

“…The majority of these studies were mainly focused on toxicity and the mechanisms of adverse effects in exposed microorganisms [7]. Only a few authors have explored the effects of nZVI on earthworms and, due to the heterogeneity of nanomaterial types (size, crystallinity, and coating), results have varied greatly [8][9][10][11][12][13][14]. Using OECD tests, some of the authors were able to observe a decrease in the viability, body weight, cocoons production, growth, and reproduction rate of earthworms after exposure to nZVI synthesized by the borohydride method [8,9,11,12].…”

Section: Introductionmentioning

confidence: 99%

“…Using OECD tests, some of the authors were able to observe a decrease in the viability, body weight, cocoons production, growth, and reproduction rate of earthworms after exposure to nZVI synthesized by the borohydride method [8,9,11,12]. However, different types of nZVI at similar concentrations did not cause any changes in earthworm viability [13,14]. Intrinsically, nZVI is a reactive material with a high reduction capacity, which can result in reactive oxygen species (ROS) generation and oxidative stress induction [15].…”

Section: Introductionmentioning

confidence: 99%

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In Vitro Study of the Toxicity Mechanisms of Nanoscale Zero-Valent Iron (nZVI) and Released Iron Ions Using Earthworm Cells

et al. 2020

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During the last two decades, nanomaterials based on nanoscale zero-valent iron (nZVI) have ranked among the most utilized remediation technologies for soil and groundwater cleanup. The high reduction capacity of elemental iron (Fe0) allows for the rapid and cost-efficient degradation or transformation of many organic and inorganic pollutants. Although worldwide real and pilot applications show promising results, the effects of nZVI on exposed living organisms are still not well explored. The majority of the recent studies examined toxicity to microbes and to a lesser extent to other organisms that could also be exposed to nZVI via nanoremediation applications. In this work, a novel approach using amoebocytes, the immune effector cells of the earthworm Eisenia andrei, was applied to study the toxicity mechanisms of nZVI. The toxicity of the dissolved iron released during exposure was studied to evaluate the effect of nZVI aging with regard to toxicity and to assess the true environmental risks. The impact of nZVI and associated iron ions was studied in vitro on the subcellular level using different toxicological approaches, such as short-term immunological responses and oxidative stress. The results revealed an increase in reactive oxygen species production following nZVI exposure, as well as a dose-dependent increase in lipid peroxidation. Programmed cell death (apoptosis) and necrosis were detected upon exposure to ferric and ferrous ions, although no lethal effects were observed at environmentally relevant nZVI concentrations. The decreased phagocytic activity further confirmed sublethal adverse effects, even after short-term exposure to ferric and ferrous iron. Detection of sublethal effects, including changes in oxidative stress-related markers such as reactive oxygen species and malondialdehyde production revealed that nZVI had minimal impacts on exposed earthworm cells. In comparison to other works, this study provides more details regarding the effects of the individual iron forms associated with nZVI aging and the cell toxicity effects on the specific earthworms’ immune cells that represent a suitable model for nanomaterial testing.

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Section: Viability Apoptosis and Necrosissupporting

confidence: 83%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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In Vitro Study of the Toxicity Mechanisms of Nanoscale Zero-Valent Iron (nZVI) and Released Iron Ions Using Earthworm Cells

et al. 2020

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“…This benefit may occur because Fe NPs provide bioavailable Fe as a nutrient, or they increase phytohormone content and antioxidant enzyme activity, but the mechanism has not been identified yet [28]. Additionally, the plant response to nZVI may vary depending on the plant species and the physicochemical properties of nZVI, such as aging, size and morphology of NPs [29,30]. To best of the authors’ knowledge, this is the first observation of the stimulation of plant growth by nZVI treatment in the soil system.…”

Section: Resultsmentioning

confidence: 99%

Effects of Zerovalent Iron Nanoparticles on Photosynthesis and Biochemical Adaptation of Soil-Grown Arabidopsis thaliana

et al. 2019

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Nanoscale zerovalent iron (nZVI) is the most widely used nanomaterial for environmental remediation. The impacts of nZVI on terrestrial organisms have been recently reported, and in particular, plant growth was promoted by nZVI treatment in various concentrations. Therefore, it is necessary to investigate the detailed physiological and biochemical responses of plants toward nZVI treatment for agricultural application. Here, the effects of nZVI on photosynthesis and related biochemical adaptation of soil-grown Arabidopsis thaliana were examined. After treatment with 500 mg nZVI/kg soil, the plant biomass increased by 38% through enhanced photosynthesis, which was confirmed by the gas-exchange system, carbon isotope ratio and chlorophyll content analysis. Besides, the iron uptake of the plant increased in roots and leaves. The magnetic property measurements and transmission electron microscopy showed that the transformed particles were accumulated in parts of the plant tissues. The accumulation of carbohydrates such as glucose, sucrose and starch increased by the enhanced photosynthesis, and photosynthetic-related inorganic nutrients such as phosphorus, manganese and zinc maintained homeostasis, according to the increased iron uptake. These findings suggest that nZVI has additional or alternative benefits as a nano-fertilizer and a promoter of CO2 uptake in plants.

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“…However, bare nZVI readily becomes aggregated and oxidized in aerobic environments, leading to a low remediation efficiency. Meanwhile, nZVI (especially in excess) will inevitably induce adverse ecological effects during the remediation process [22][23][24][25]. For instance, nZVI generally exhibits "low-dose stimulation and high-dose inhibition" effects on plant growth via multiple mechanisms [22].…”

Section: Introductionmentioning

confidence: 99%

Remediation of Cr(VI)-Contaminated Soil by Nano-Zero-Valent Iron in Combination with Biochar or Humic Acid and the Consequences for Plant Performance

Sun

Zheng

Wang

et al. 2020

Toxics

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Nano-scale zero-valent iron (nZVI) is among the most common nanoparticles widely used for the treatment of various environmental contaminants. However, little is known about the combined effects of nano-zero-valent iron (nZVI) and other soil amendments on soil remediation and plant performance. For the first time, we studied the remediation of Cr(VI)-contaminated soil using bare nZVI (B-nZVI) and starch-supported nZVI (S-nZVI) in combination with either biochar (BC) or humic acid (HA), and the consequent effects on plant growth and Cr accumulation. Both S-nZVI and B-nZVI decreased the contents of Cr(VI) and available Cr in soil, but increased available Fe content, with S-nZVI generally showing more pronounced effects at a higher dose (1000 mg/kg). B-nZVI exerted no inhibition and even stimulation on plant growth, but 1000 mg/kg S-nZVI produced significant phytotoxicity, resulting in decreased plant growth, low chlorophyll content in leaves, and excessive accumulation of Fe in roots. Each nZVI decreased shoot and root Cr concentrations. BC and HA produced synergistic effects with nZVI on Cr(VI) removal from soil, but HA decreased soil pH and increased the availability of Cr and Fe, implying a potential environmental risk. Addition of BC or HA did not alter the effects of either nZVI on plant growth. In conclusion, combined application of 100 mg/kg nZVI and BC could be an ideal strategy for the remediation of soil contaminated with Cr(VI), whereas high-dose S-nZVI and HA are not recommended in the remediation of agricultural soils for crop production or in the phytostabilization of Cr(VI).

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Impact of surface modification on the toxicity of zerovalent iron nanoparticles in aquatic and terrestrial organisms

Cited by 43 publications

References 38 publications

In Vitro Study of the Toxicity Mechanisms of Nanoscale Zero-Valent Iron (nZVI) and Released Iron Ions Using Earthworm Cells

In Vitro Study of the Toxicity Mechanisms of Nanoscale Zero-Valent Iron (nZVI) and Released Iron Ions Using Earthworm Cells

Effects of Zerovalent Iron Nanoparticles on Photosynthesis and Biochemical Adaptation of Soil-Grown Arabidopsis thaliana

Remediation of Cr(VI)-Contaminated Soil by Nano-Zero-Valent Iron in Combination with Biochar or Humic Acid and the Consequences for Plant Performance

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