Impact of surgical wait time on postoperative and oncological outcomes in resectable pancreas adenocarcinoma

Abstract

range = 20e8,500 mL), length of stay was 8 days (range = 3e162 days), and the overall grade 3 or 4 complication rate was 22% (23% after PD and 18% after DP). Univariate analysis revealed increasing age (HR 1.02), increasing tumor size (HR 1.01), positive margins (HR 1.48), positive lymph nodes (HR 1.79), increasing number of positive lymph nodes (HR 1.07 per node), and EBL (HR 1.02 per 100 mL) to be associated with OS. Multivariate analysis concluded that age, tumor size, margin status, the number of positive lymph nodes, and EBL were predictive of OS, and were included in the nomogram (Figure), for which the concordance index was 0.62. Conclusion: Using a large, prospectively maintained registry of patients undergoing resection for PDAC, a nomogram prognostic of 1-, 3-, and 5-year survival was generated. Criteria for pathologic staging, namely tumor size and nodal burden, remain the most important predictors of long-term survival.