Impact of the 2016 ASE/EACVI Guidelines on diastolic function reporting in routine clinical practice

Gopalakrishnan, Prabhakaran; Biederman, Robert W

doi:10.1111/echo.14645

Cited by 3 publications

(2 citation statements)

References 33 publications

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“…Hence, they concluded that the application of the new recommendations resulted in a much lower prevalence of LVDD and that the concordance between the classifications was poor. In a recent study by Gopalakrishnan et al, that also followed the 2016 ASE/EACVI recommendations and was based on more than 20,000 echocardiograms from a single-center, it was demonstrated that there was a 57% decrease in reporting of diastolic dysfunction (p<0.001), grade 1 LVDD decreased by 64% (P < 0.001), grade 2 LVDD decreased by 51% (P <0.001), and grade 3 LVDD did not change significantly (P =0.18) [11]. Hence, diastolic function studies published before the release of the 2016 recommendations present miscellaneous non-standardized results.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Outcome of Advanced Left Ventricular Diastolic Dysfunction among Consecutive Patients Referred for Echocardiography

Moriel¹,

Butnaru²,

Klutstein³

et al. 2021

JICOA

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Aim: To assess the prevalence of advanced left ventricular diastolic dysfunction (LVDD) in a cohort of consecutive patients referred for echocardiography and its association with mortality. Methods: The cohort included 4,481 (85% hospitalized) patients who underwent echocardiography, had normal or preserved LV systolic function and diastolic function assessment. LVDD was graded as none or mild (0/I) and advanced grade (II/III). Mortality data were derived from the National Israeli Population Registry. Results: LVDD grade II/III was found in 1,262 patients (28%), was more prevalent among the elderly, females, diabetic and hypertensive patients. Independent predictors associated with LVDD grade II/III (OR; 95% CI) were: age (1-year increment) 1.015 (1.01-1.02), p<0.001; female sex 1.2 (1.04-1.39), p=0.012; hypertension 1.53 (1.30-1.80), p<0.001, while ischaemic heart disease was negatively associated 0.73 (0.63- 0.85), p<0.001. 1-year mortality rates were higher among grade II/III LVDD as compared to grade 0/I DD patients, 19% vs. 10.2%, respectively, p<0.0001. Independent predictors for all-cause mortality after adjusting for pertinent variables were: LVDD grade II/III 1.72 (1.40-2.11); age (1-year increment) 1.08 (1.07-1.09) and diabetes 1.54 (1.26-1.70), p<0.001 for all. Conclusion: LVDD grade II/III was more prevalent among the elderly, females, diabetic and hypertensive patients. Advanced LVDD was a strong independent predictor for all-cause mortality after adjustment for risk factors. Intensive pharmacological therapies at an earlier stage of LVDD may improve patients’ outcome.

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Section: Discussionmentioning

confidence: 99%

Prevalence and Outcome of Advanced Left Ventricular Diastolic Dysfunction among Consecutive Patients Referred for Echocardiography

Moriel¹,

Butnaru²,

Klutstein³

et al. 2021

JICOA

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“…For example, larger LA volumes and lower strain and LA EF were independent predictors of AF development in recent studies [ 4 , 5 ], including sub-clinical AF [ 6 ]. LA function may improve the diagnostic accuracy and prognostic value of diastolic dysfunction in magnetic resonance imaging (MRI) [ 7 ]. LA evaluation plays an important role in imaging of AF, stroke risk related to AF, and diastolic dysfunction evaluation [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Automated left atrial time-resolved segmentation in MRI long-axis cine images using active contours

et al. 2021

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Background Segmentation of the left atrium (LA) is required to evaluate atrial size and function, which are important imaging biomarkers for a wide range of cardiovascular conditions, such as atrial fibrillation, stroke, and diastolic dysfunction. LA segmentations are currently being performed manually, which is time-consuming and observer-dependent. Methods This study presents an automated image processing algorithm for time-resolved LA segmentation in cardiac magnetic resonance imaging (MRI) long-axis cine images of the 2-chamber (2ch) and 4-chamber (4ch) views using active contours. The proposed algorithm combines mitral valve tracking, automated threshold calculation, edge detection on a radially resampled image, edge tracking based on Dijkstra’s algorithm, and post-processing involving smoothing and interpolation. The algorithm was evaluated in 37 patients diagnosed mainly with paroxysmal atrial fibrillation. Segmentation accuracy was assessed using the Dice similarity coefficient (DSC) and Hausdorff distance (HD), with manual segmentations in all time frames as the reference standard. For inter-observer variability analysis, a second observer performed manual segmentations at end-diastole and end-systole on all subjects. Results The proposed automated method achieved high performance in segmenting the LA in long-axis cine sequences, with a DSC of 0.96 for 2ch and 0.95 for 4ch, and an HD of 5.5 mm for 2ch and 6.4 mm for 4ch. The manual inter-observer variability analysis had an average DSC of 0.95 and an average HD of 4.9 mm. Conclusion The proposed automated method achieved performance on par with human experts analyzing MRI images for evaluation of atrial size and function.

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Right ventricular diastolic function in post-surgical Tetralogy of Fallot patients: A pilot study to make a comparison between echocardiography and cardiac MRI

Bassareo

Deidda

Calcaterra

et al. 2021

International Journal of Cardiology Congenital Heart Disease

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Impact of the 2016 ASE/EACVI Guidelines on diastolic function reporting in routine clinical practice

Cited by 3 publications

References 33 publications

Prevalence and Outcome of Advanced Left Ventricular Diastolic Dysfunction among Consecutive Patients Referred for Echocardiography

Prevalence and Outcome of Advanced Left Ventricular Diastolic Dysfunction among Consecutive Patients Referred for Echocardiography

Automated left atrial time-resolved segmentation in MRI long-axis cine images using active contours

Right ventricular diastolic function in post-surgical Tetralogy of Fallot patients: A pilot study to make a comparison between echocardiography and cardiac MRI

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