Impact of the COVID-19 pandemic on clinical research

Informed Consent for Scholarly Articles during the COVID-19 Pandemic

“… 17 From a research point of view, the biggest impact is related to the shift of resource distribution towards clinical research, primarily focused on disease treatment, with intentions to bring relief to the pandemic. 18 19 Another important aspect to consider is the shortage of researchers and physicians, mainly due to the dual responsibility of providing treatment and care to patients while investigating. 17 As far as the informed consent, changes in protocols and recommendations to decrease disease transmission generated tension between society and healthcare institutions.…”

Perspectives from the Society for Pediatric Research: advice on sustaining science and mentoring during COVID-19

“…Social distancing guidelines have disrupted both forms of research with implementation strategies ranging from limiting personnel in laboratories to complete shut-downs or pausing all clinical research and non-emergent clinical work. 15 Personal disruptions from COVID-19 (personal or family illnesses, childcare needs including stay-at-home school age children, etc.) also factor significantly into decreased productivity.…”

Perioperative Cardiac Research Considerations During the Coronavirus Disease 2019 (COVID-19) Pandemic

“…At the beginning of the pandemic, many trials were forced to close abruptly, experiments were discarded, laboratories were temporarily shut down, and investigators became hesitant to start long term studies due to the fear of potential lockdowns. 1 , 2 As of August, 2020, there remained a 20% decline from pre-COVID baseline in new patients entering cardiovascular trials, although this number is significantly improved from the 97% decline as reported in April 2020. 3 Recovery continues to vary greatly by geographic region and the research environment due to the varying impact of the disease as well as the local policies and responses that have adapted over time.…”