2021
DOI: 10.1080/17476348.2021.1951707
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Impact of the COVID-19 pandemic on the management of chronic noninfectious respiratory diseases

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Cited by 18 publications
(12 citation statements)
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“…42 Consistently, in a stratified cohort of asthmatics the expression of the ACE2 in the bronchial epithelium was inversely correlated with peripheral blood eosinophil counts. 43 ACE2 receptor expression is linked to upregulation of viral response genes in a subset of type 2low patients with asthma with characteristics resembling known risk factors for severe coronavirus disease 2019 (1). In asthmatics, pre-existing eosinophilia (AEC!150 cells/mL) was protective from COVID-19-associated admission, and development of eosinophilia (AEC!150 cells/mL) during hospitalization was associated with decreased mortality.…”
Section: Asthma and Allergies Epidemiologymentioning
confidence: 99%
See 1 more Smart Citation
“…42 Consistently, in a stratified cohort of asthmatics the expression of the ACE2 in the bronchial epithelium was inversely correlated with peripheral blood eosinophil counts. 43 ACE2 receptor expression is linked to upregulation of viral response genes in a subset of type 2low patients with asthma with characteristics resembling known risk factors for severe coronavirus disease 2019 (1). In asthmatics, pre-existing eosinophilia (AEC!150 cells/mL) was protective from COVID-19-associated admission, and development of eosinophilia (AEC!150 cells/mL) during hospitalization was associated with decreased mortality.…”
Section: Asthma and Allergies Epidemiologymentioning
confidence: 99%
“…Several underlying conditions have been associated with the virus, and whether underlying asthma is associated with worse COVID-19 outcomes has been extensively analyzed. 1…”
Section: Introductionmentioning
confidence: 99%
“…SARS-CoV-2 pandemic had a general and deep impact on the clinical management of most chronic diseases in adults and children. 1,2 Especially in the first phases of this pandemic, a great concern was the potential effect of concomitant immunosuppressive/immunomodulatory therapies on the individual susceptibility, clinical course, and outcome of COVID-19. 3 Rheumatic disorders immediately received a great attention to understand if the biological therapies could worsen the clinical course of COVID-19.…”
Section: Introductionmentioning
confidence: 99%
“…The coronavirus disease 2019 (COVID-19) pandemic has infected millions of people around the globe [ [1] , [2] , [3] , [4] , [5] ]. The initial symptoms of COVID-19 are similar to other respiratory diseases, but some patients can be asymptomatic [ 6 ] or presenting with milder symptoms due to the success of the vaccination programme [ 7 ]. Therefore, tracking the causative SARS-CoV-2 is a difficult task.…”
Section: Introductionmentioning
confidence: 99%