An earthquake is a natural disaster with a high destructive force. According to previous history, a great many power grid facilities are damaged during the earthquake, and the damage to electrical equipment in substations are often very serious. This article takes the isolating switch in the substation as an experimental object. Firstly, the friction pendulum for vibration isolation is designed and manufactured according to the numerical simulation, and then the seismic test and vibration isolation test of the high voltage isolating switch are designed. The input waveforms and input acceleration intensities of the seismic test were designed experimentally. The test data of the isolating switch under the seismic condition and the vibration isolation condition with the friction pendulum vibration isolation system installed are mainly investigated. The measured acceleration of the top of the isolating switch bracket is used to compare and analyze the vibration isolation performance of the friction pendulum. Then, it can be seen that the friction pendulum system has the vibration isolation effects on the isolating switch. Especially, the isolation effects of friction pendulum are better when the acceleration intensity become higher. In order to obtain a better curvature radius and friction coefficient of the friction pendulum, based on the results of this test, the systematically numerical simulation tests for optimization on the friction pendulum vibration isolation system are conducted. The simulated top displacement of the isolating switch and the stress change of the root of the porcelain bottle were obtained. By comparing the vibration isolating performance of the friction pendulum under different parameters, numerical simulations show that the vibration isolation performance of the friction pendulum is better when the radius of curvature is 1200 mm and the friction coefficient is 0.04. The numerical results demonstrate that reasonable design of friction pendulum parameters can play a significant role in isolating vibration for power equipment.