Impact of the Neutrophil-to-Lymphocyte Ratio in Patients With Coronary Artery Disease

Buğan, Barış; Onar, Lutfi Cagatay; Yalcinkaya, Emre

doi:10.1177/1076029613496313

Cited by 2 publications

(2 citation statements)

References 4 publications

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“…We appreciate the constructive comments of Bugan et al 1 on our manuscript ''Association between Neutrophil-to-Lymphocyte Ratio and Severity of Coronary Artery Disease.'' 2 As a response to their first comment, we have performed multivariate logistic regression analysis to assess the independent predictors of the severity of coronary artery disease (CAD) which revealed neutrophil-to-lymphocyte ratio (NLR) as the independent predictor of CAD severity; therefore, fasting glucose, highdensity lipoprotein cholesterol, and creatinine values may not influence the NLR.…”

mentioning

confidence: 94%

Association Between Neutrophil to Lymphocyte Ratio and Severity of Coronary Artery Disease

Kaya

Ertaş

Soydinç

2013

Clin Appl Thromb Hemost

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confidence: 94%

Association Between Neutrophil to Lymphocyte Ratio and Severity of Coronary Artery Disease

Kaya

Ertaş

Soydinç

2013

Clin Appl Thromb Hemost

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“…The NLR is calculated by dividing the number of neutrophils by the number of lymphocytes in the blood. Several studies have shown that the NLR is a strong predictor of adverse outcomes in both stable and unstable CAD, as well as in patients undergoing coronary revascularization procedures such as coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) [ 4 , 5 ]. However, the exact role of the NLR in acute ST-segment elevation myocardial infarction (STEMI), which is the most severe form of CAD, is still unclear.…”

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confidence: 99%

The Impact of the Neutrophil-to-Lymphocyte Ratio on In-Hospital Outcomes in Patients With Acute ST-Segment Elevation Myocardial Infarction

Karaca,

Ekmekci,

Kimiaei

et al. 2024

Cureus

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Introduction The neutrophil-to-lymphocyte ratio (NLR) is a significant predictor of cardiovascular diseases, influencing their progression and prognosis. The exact role of the NLR in acute ST-segment elevation myocardial infarction (STEMI) is unclear. We investigated the possible association between peak NLR values within the first three days after STEMI onset and in-hospital outcomes in patients undergoing primary percutaneous coronary intervention (PCI). Methods This retrospective study included 641 patients who were diagnosed with acute STEMI and treated with primary PCI for 18 months at Dr. Siyami Ersek Hospital. The NLR was calculated using the maximum values obtained during the first three days after admission. The patients were divided into quartiles according to their NLR values for further analysis of potential complications during and after hospitalization, up to a follow-up period of three months. Results Significant differences were found in factors such as age, body mass index (BMI), and length of hospital stay among these groups. Specifically, we found that in-hospital mortality rates were significantly higher in the Q4 group, and there were variations in target vessel revascularization (TVR) rates, major adverse cardiac events (MACE) rates, and other clinical outcomes. Some parameters, such as reinfarction rates and certain procedural outcomes, did not show significant differences among the groups. However, despite the differences, most of the patients achieved successful outcomes after PCI, with the best results in the low NLR group and the worst results in the high NLR group. Conclusion Higher NLR values were associated with a higher risk of unfavorable outcomes during hospitalization.

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Impact of the Neutrophil-to-Lymphocyte Ratio in Patients With Coronary Artery Disease

Cited by 2 publications

References 4 publications

Association Between Neutrophil to Lymphocyte Ratio and Severity of Coronary Artery Disease

Association Between Neutrophil to Lymphocyte Ratio and Severity of Coronary Artery Disease

The Impact of the Neutrophil-to-Lymphocyte Ratio on In-Hospital Outcomes in Patients With Acute ST-Segment Elevation Myocardial Infarction

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