The fire incidences in Campo Grande have been a serious environmental problem. Therefore, this study is aimed at studying the trend of acute respiratory infections (IRA) from the year 2011 to 2017 and to correlate it with precipitation, wind speed, relative humidity, maximum and minimum temperatures, surface ozone concentration, optical depth, index of clarity and the number of outbreaks of fires. IRA records were obtained through DATASUS; the record of burn outbreaks at the National Institute for Space Research and the ozone concentration at the Federal University of Mato Grosso do Sul. There exists a positive and significant correlation between the number of burn outbreaks, wind velocity, ozone concentration, and optical depth with rates of hospitalizations for IRA. Also, a negative correlation exists between precipitation parameters, relative humidity, maximum and minimum temperatures. These results show the intensity of the problem and the great impact on the respiratory health of the population as well as on the economy due to increase in the number of hospitalizations and days of treatment.Climate can affect air quality, which in turn can affect climate change and both can directly or indirectly affect health. The two main effects of climate change on air quality are degrading the processes of removal (dispersion, precipitation) and atmospheric chemistry [3]. These will affect primary pollutants (e.g soot particles) and secondary pollutants (e.g ozone and sulfate particles) [4,5].The lack of information regarding the relation between atmospheric pollution and climatic variations and respiratory infections in the cities instigated the verification of this relation. Thus, the objective of the present study is to verify the relationship between climatic variation and atmospheric pollution, on one side, and the number of hospitalizations due to respiratory diseases in the population of the city of Campo Grande-MS.Climate indicators and the impact on morbidity and mortality 7