2021
DOI: 10.1155/2021/8727924
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Impacts of Chemokine (C-X-C Motif) Receptor 2 C1208T Polymorphism on Cancer Susceptibility

Abstract: Background. The CXC chemokines belong to a unique family of cytokines that participates in the progression and development of many malignant tumors. Evidence for the relationship between chemokine (C-X-C motif) receptor 2 (CXCR2) C1208T polymorphism and susceptibility to cancer remains inconsistent. Methods. Odds ratios (ORs), 95% confidence intervals (CIs), and combined analysis were used to investigate the effect of CXCR2 variation on cancer risk. Gene Set Enrichment Analysis (GSEA) and enzyme-linked immunos… Show more

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Cited by 3 publications
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“…One possible reason might be that most of the authors who performed the pooled analysis were from Asian countries. They tended to publish positive results related to their own ethnicity [50–53] . Moreover, the number of studies based on African populations included in current analysis was fairly few.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…One possible reason might be that most of the authors who performed the pooled analysis were from Asian countries. They tended to publish positive results related to their own ethnicity [50–53] . Moreover, the number of studies based on African populations included in current analysis was fairly few.…”
Section: Discussionmentioning
confidence: 99%
“…They tended to publish positive results related to their own ethnicity. [50][51][52][53] Moreover, the number of studies based on African populations included in current analysis was fairly few. Different conclusions may be drawn by increasing the sample size.…”
Section: Discussionmentioning
confidence: 99%