2007
DOI: 10.1093/bja/aem280
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Impaired vitamin B12 metabolic status in healthcare workers occupationally exposed to nitrous oxide

Abstract: Exposure to N(2)O in healthcare workers is associated with alterations of vitamin B12 metabolic status, the extent of which depends on the level of exposure.

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Cited by 46 publications
(34 citation statements)
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“…According to the recent well-documented reports, it is well known that N 2 O causes Hyperhomocysteinemia (tHcy) which is a risk factor for bad pregnancy outcome (2,10,12,15,16). We hypothesized that occupational exposure to N 2 O causes tHcy and this is a risk factor for recurrent early pregnancy loss.…”
Section: Discussionmentioning
confidence: 99%
“…According to the recent well-documented reports, it is well known that N 2 O causes Hyperhomocysteinemia (tHcy) which is a risk factor for bad pregnancy outcome (2,10,12,15,16). We hypothesized that occupational exposure to N 2 O causes tHcy and this is a risk factor for recurrent early pregnancy loss.…”
Section: Discussionmentioning
confidence: 99%
“…Bununla birlikte Watcha ve ark. (17) 'da benzer şekilde N 2 O ile anestezi uygulanan olgularda, hafif hemotolojik deği-şikliklerden agranülositozis, spinal kord dejenerasyonu ve polinöropatiye kadar değişen komplikasyonlar bildirmiştir. N 2 O'e bağlı nörolojik komplikasyonların insidansı ve komplikasyon oluşturması için gerekli minimum maruziyet süresi bilinmemektedir (18) .…”
Section: Discussionunclassified
“…11,21 The biochemical effects of NO as an anesthetic agent have long been studied, but not entirely understood. 9,10,12,13,20,29,30 It's effects on the spinal cord have been recognized since 1959 by Randt, in laboratory studies in cats. 26 NO abuse tends to present clinically with a predominant effect on the dorsal columns.…”
Section: Discussionmentioning
confidence: 99%