2015
DOI: 10.1002/jbm.b.33463
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Implant design and its effects on osseointegration over time within cortical and trabecular bone

Abstract: Healing chambers present at the interface between implant and bone have become a target for improving osseointegration. The objective of the present study was to compare osseointegration of several implant healing chamber configurations at early time points and regions of interest within bone using an in vivo animal femur model. Six implants, each with a different healing chamber configuration, were surgically implanted into each femur of six skeletally mature beagle dogs (n = 12 implants per dog, total n = 72… Show more

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Cited by 32 publications
(41 citation statements)
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“…BIC and BAFO are long established measures for osseointegration in scientific literature (7,8,10,11,(16)(17)(18)(19)(20). BAFO reflects the bone occupancy rate, which can be filled by newly formed bone via distance osteogenesis or contact osteogenesis, such as for bone fragments compressed between bone wall.…”
Section: Discussionmentioning
confidence: 99%
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“…BIC and BAFO are long established measures for osseointegration in scientific literature (7,8,10,11,(16)(17)(18)(19)(20). BAFO reflects the bone occupancy rate, which can be filled by newly formed bone via distance osteogenesis or contact osteogenesis, such as for bone fragments compressed between bone wall.…”
Section: Discussionmentioning
confidence: 99%
“…The implant design, the healing chamber dimensions and type of bone (cortical or trabecular) exert strong effect on osseointegration over time (20). It is recognized that drilling protocol (oversized, intermediate or undersized) result in different biological responses with higher BIC and BAFO values for intermediate drilling (22).…”
Section: Discussionmentioning
confidence: 99%
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“…It is essential to generate a stable mechanical bond between implant and host bone by direct bone/implant contact. Osseointegration, as a direct structural and functional connection between the living bone and the surface of an implant, was the focus of several studies . Integrity of the bond between bone and implant, and the amount of bone surrounding the implant acting as the implant stabilizer, are the vital determinants of an implant success …”
Section: Introductionmentioning
confidence: 99%
“…Osseointegration, as a direct structural and functional connection between the living bone and the surface of an implant, 3 was the focus of several studies. [4][5][6][7] Integrity of the bond between bone and implant, and the amount of bone surrounding the implant acting as the implant stabilizer, are the vital determinants of an implant success. 8,9 In a well-designed implant system, the mechanical and biological compatibility and integration of the implant with the surrounding bone should be considered.…”
Section: Introductionmentioning
confidence: 99%