“…Parameters concerning the rate and extent of osseointegration have been scrutinized with considerable scientific effort over the past 3 decades. Well-recognized factors that support implant osseointegration include: the incorporation of a micrometer and/or nanometer scale surface topography (Lintner et al, 1986;Albrektsson and Wennerberg, 2005;Aldinger et al, 2009;Wennerberg and Albrektsson, 2009), close proximity of implant to the bone surface (Sandborn et al, 1988), implant stability (repetitive motion less than 150 um) (Engh et al, 1992;Kienapfel et al, 1999;Sakka and Coulthard, 2011), implant material (Jinno et al, 1998;Jakobsen et al, 2010) and cleanliness (Esposito et al, 1999;Elias and Meirelles, 2010).…”