2019
DOI: 10.3390/jcm8050722
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Implant Fixation and Risk of Prosthetic Joint Infection Following Primary Total Hip Replacement: Meta-Analysis of Observational Cohort and Randomised Intervention Studies

Abstract: Prosthetic joint infection (PJI), although uncommon, is a dreaded and devastating complication of total hip replacement (THR). Whether implant-related factors, such as the fixation method, influences the risk of PJI following THR is contentious. We conducted a systematic review and meta-analysis to evaluate the body of evidence linking fixation methods (cemented, uncemented, hybrid, or reverse hybrid) with the risk of PJI following primary THR. Observational studies and randomised controlled trials (RCTs) comp… Show more

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Cited by 25 publications
(24 citation statements)
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“…The top three comparison studies focused on cemented vs. cementless total joint arthroplasty, the outcome of using different types of spacers, and the outcome of one-stage vs. two-stage exchange. Cemented fixations were revealed to increase the overall PJI risk in comparison to uncemented fixations [66][67][68]. Interestingly, there was no significant difference in the eradication rate between articulating and static spacers in the infected knee replacement [69,70].…”
Section: Discussionmentioning
confidence: 97%
“…The top three comparison studies focused on cemented vs. cementless total joint arthroplasty, the outcome of using different types of spacers, and the outcome of one-stage vs. two-stage exchange. Cemented fixations were revealed to increase the overall PJI risk in comparison to uncemented fixations [66][67][68]. Interestingly, there was no significant difference in the eradication rate between articulating and static spacers in the infected knee replacement [69,70].…”
Section: Discussionmentioning
confidence: 97%
“…The top three comparison studies focused on cemented vs. cementless total joint arthroplasty, the outcome of using different types of spacers, and the outcome of one-stage vs. two-stage exchange. Cemented fixations were revealed to increase the overall PJI risk in comparison to uncemented fixations [34][35][36]. Interestingly, there was no significant difference in the eradication rate between articulating and static spacers in the infected knee replacement [37,38].…”
Section: Discussionmentioning
confidence: 97%
“…Cemented fixations were revealed to increase the overall PJI risk in comparison to uncemented fixations [18][19][20]. Interestingly, there was no significant difference in the eradication rate between articulating and static spacers in the infected knee replacement [21,22].…”
Section: Comparative Analysismentioning
confidence: 97%
“…The majority of papers were published in March (10), August (9), and January (8), and on the weekdays Thursday (19), Friday 16…”
Section: First Authormentioning
confidence: 99%