Implant therapy for a patient with osteogenesis imperfecta type I: review of literature with a case report

Abstract

Bone fragility and skeletal irregularities are the characteristic features of osteogenesis imperfecta (OI). Many patients with OI have weakened maxillary and mandibular bone, leading to poor oral hygiene and subsequent loss of teeth. Improvements in implant therapy have allowed for OI patients to achieve dental restoration. However, there is limited available literature on implant therapy for patients with OI. The greatest challenge in the restoration process for OI patients in an outpatient setting is ensuring primary stability and osseointegration. Improvements in synthetic grafts improve successful implant placement and prevent predisposing patients to unnecessary procedures. This report details the successful restoration process of an OI type I patient’s maxillary arch in addition to a review of the currently available literature.

Dental implant considerations in patients with systemic diseases: An updated comprehensive review

“…Besides the skeletal phenotype, other extra‐skeletal manifestations are vascular fragility, blue sclerae, dentinogenesis imperfecta (DI) and hearing loss. Effective implant therapy has previously been described in some case reports for OI cases 178,389–399 . Effective implant therapy for OI patients was reported in a retrospective analysis, with a survival rate ranging from 93% to 100% 395 .…”

“…Effective implant therapy has previously been described in some case reports for OI cases. 178,[389][390][391][392][393][394][395][396][397][398][399] Effective implant therapy for OI patients was reported in a retrospective analysis, with a survival rate ranging from 93% to 100%. 395 Analysing the data pertinent to 23 patients with a total of 116 implants in a systematic review revealed an implant survival rate of 94.0% with a mean follow-up of 59.1 months.…”

Implant-Prosthetic Restoration of a Patient with Osteogenesis Imperfecta: A Case Report

“…To date, only a few case reports have been published on implant-prosthetic restorations in patients with OI [ 10 , 16 , 17 , 18 , 19 , 20 , 21 , 22 ]. A Norwegian study reported a 95.7% survival rate of implants in patients with OI 25–135 months after prosthetic loading [ 22 ].…”

“…A Norwegian study reported a 95.7% survival rate of implants in patients with OI 25–135 months after prosthetic loading [ 22 ]. Successful augmentative procedures using autologous retromolar bone, corticospongous grafts of the iliac crest and synthetic substitutes have also been reported [ 10 , 11 , 16 , 17 , 18 ]. Thus, although the relevant data remain limited, the use of implants and augmentative measures in patients with OI seems to be safe and achievable in principle, without any major limitations.…”

“…The mildest form of OI is considered to be OI type I, in which collagen type I is of normal quality but reduced quantity [ 9 ]. To date, there have only been a few case reports of implant-prosthetic restorations in patients with OI [ 10 , 11 ].…”