Implementation of Contrast-Enhanced Mammography in Clinical Practice

Kaur, Maninderpal; Piccolo, Claudia Lucia; Arasaratnam, Shantini

doi:10.1007/978-3-319-94553-8_7

Cited by 2 publications

(3 citation statements)

References 28 publications

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“…ontrast-enhanced digital mammography (CEDM) is a new technique in which full-field digital mammography (FFDM) is supplemented with the use of intravenous iodinated contrast administration. In this technique, contrast-enhanced digitally subtracted images are used to assess the tumor neo-angiogenesis, in a similar manner as in contrast-enhanced magnetic resonance imaging (MRI), with near complete subtraction of background parenchyma (1)(2)(3). Tumor neo-angiogenesis occurs due to increased formation of small random blood vessels within the mass, which are more permeable to contrast media resulting in tumor enhancement after administration of iodinated contrast media compared with the surrounding normal breast tissue (3,4).…”

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“…In this technique, contrast-enhanced digitally subtracted images are used to assess the tumor neo-angiogenesis, in a similar manner as in contrast-enhanced magnetic resonance imaging (MRI), with near complete subtraction of background parenchyma (1)(2)(3). Tumor neo-angiogenesis occurs due to increased formation of small random blood vessels within the mass, which are more permeable to contrast media resulting in tumor enhancement after administration of iodinated contrast media compared with the surrounding normal breast tissue (3,4). Contrast enhancement can be seen in both benign and malignant tumors; however, it tends to be more frequent and intense in malignant tumors compared with benign ones (5,6).…”

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Technique and clinical applications of dual-energy contrast-enhanced digital mammography (CEDM) in breast cancer evaluation: a pictorial essay

Sudhir¹,

Koppula²,

Mandava³

et al. 2021

Diagn Interv Radiol

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Contraindications to CEDMCEDM should be avoided in pregnant women, those with history of allergy to iodinated contrast media, and those with renal insufficiency. Contrast administrationA trained technologist obtains the peripheral intravenous access preferably using a 18-gauge needle. A dose of 1.5 mL/kg bodyweight of iodinated contrast media (Omnipaque ABSTRACT This pictorial essay illustrates an overview of the basic technique used in acquiring dual-energy contrast-enhanced digital mammography (CEDM) images and its potential clinical applications in regular practice. CEDM may be used as a low-cost alternative to magnetic resonance imaging (MRI), as a problem-solving tool in clinical practice and for therapeutic planning of breast cancer, which may include high-risk screening, dense breast evaluation, mammographically equivocal lesions, local staging, treatment response evaluation, and post treatment follow-up. We share our experience of CEDM at a tertiary care cancer hospital.

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Technique and clinical applications of dual-energy contrast-enhanced digital mammography (CEDM) in breast cancer evaluation: a pictorial essay

Sudhir¹,

Koppula²,

Mandava³

et al. 2021

Diagn Interv Radiol

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“…Therefore, CEDM may be a suitable low-cost alternative in women with dense breasts or among those who have a higher-than-average lifetime risk of breast cancer, especially when MRI is not available or cannot be performed. while this technique may be useful for indications previously reserved for MRI, such as problem solving, determining the extent of disease in newly diagnosed cancer patients, monitoring response to neoadjuvant therapy, evaluating post-treatment breast screening to detect residual or recurrent disease and potentially screening women at intermediate or high risk for breast cancer [25].…”

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Use of mammography with contrast for the diagnosis of breast cancer

Estrada¹,

Muñoz²,

Ricardo³

et al. 2022

World J. Adv. Res. Rev.

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Breast cancer is a heterogeneous disease, caused by the progressive accumulation of mutations and chromosomal abnormalities. Currently, breast cancer is considered the neoplasm with the highest incidence and mortality in women worldwide, so much so that every year in the world, one million breast cancers are discovered and around 400,000 women die from it. The search for diagnostic techniques that allow the detection of this pathology in an effective way has become essential and that is where mammography emerges, as a screening method, which has been shown to reduce mortality by detecting breast cancer early; however, in very dense breasts detection is difficult, so they have been modified, and thus generating new screening and diagnostic methods such as contrast-enhanced mammography, which is the newest and most promising imaging technique based on neovascularization of breast tumors in a similar way and may even be better than MRI.

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Implementation of Contrast-Enhanced Mammography in Clinical Practice

Cited by 2 publications

References 28 publications

Technique and clinical applications of dual-energy contrast-enhanced digital mammography (CEDM) in breast cancer evaluation: a pictorial essay

Technique and clinical applications of dual-energy contrast-enhanced digital mammography (CEDM) in breast cancer evaluation: a pictorial essay

Use of mammography with contrast for the diagnosis of breast cancer

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