To thrive in multicultural workplace settings, it is essential to understand how individuals from different cultural backgrounds communicate and share meaning. Higher education institutions (HEIs), through international academic collaborations, are uniquely positioned to cultivate a skilled workforce capable of addressing contemporary global challenges. Beyond fostering cultural awareness, a critical and analytical approach has become integral to modern higher education, ensuring a rigorous and versatile learning environment that promotes respect for diverse needs and rights. This chapter provides a critical analysis of the factors shaping the internationalisation of higher education within the Global North and South. It examines current trends in curriculum internationalisation and suggests strategies to enhance global competence among graduates. In an era defined by open science and advancements in artificial intelligence (AI), issues of equality, diversity, and inclusion (EDI) have taken centre stage in education. This chapter proposes a Universal Design for Learning (UDL) framework to address these challenges and demonstrate how socio-cultural and geopolitical perspectives can be harnessed to promote internationalisation within higher education curricula. The chapter concludes by emphasising the need for HEIs to prioritise internationalisation and incorporate global learning strategies to meet the demands of the 21st century and the Fourth Industrial Revolution (4IR).