Importance of clinical history in the diagnosis of psittacosis: A case report

Khadka, Sulochana; Timilsina, Bibek; Pangeni, Raju; Regmi, Pradeep Raj; Thapa, Anupam Singh

doi:10.1016/j.amsu.2022.104695

Cited by 3 publications

(2 citation statements)

References 16 publications

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“… 20 Elevated erythrocyte sedimentation rate and CRP levels are common laboratory parameters for diagnosing psittacosis. 21 In this case, the increased WBC and neutrophil counts and elevated CRP levels indicated that the patient may have been infected with C. psittaci on admission. However, it is unknown which infection occurred first in this case.…”

Section: Discussionmentioning

confidence: 72%

Pneumonia Caused by Chlamydia psittaci and SARS-CoV-2 Coinfection Diagnosed Using Metagenomic Next-Generation Sequencing: A Case Report

Zhang,

Liang,

Lao

et al. 2024

IMCRJ

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We report a case of pneumonia caused by coinfection with Chlamydia psittaci and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron XBB.1 variant, confirmed using metagenomic next-generation sequencing (mNGS) and quantitative polymerase chain reaction (qPCR). C. psittaci and SARS-CoV-2 were detected in bronchoalveolar lavage fluid using mNGS. Additionally, mNGS detected C. psittaci in blood and nasopharyngeal specimens and was more sensitive than qPCR. The patient recovered after treatment with moxifloxacin. This report highlights the use of coinfections of C. psittaci and SARS-CoV-2, as mNGS has already been recognized to be a diagnostic tool for identifying coinfections.

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Section: Discussionmentioning

confidence: 72%

Pneumonia Caused by Chlamydia psittaci and SARS-CoV-2 Coinfection Diagnosed Using Metagenomic Next-Generation Sequencing: A Case Report

Zhang,

Liang,

Lao

et al. 2024

IMCRJ

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“…Handling the feathers, tissues, or corpses of infected birds also carries a risk of infection[ 1 ]. The first description of psittacosis in the medical literature was in 1879[ 2 ], and according to subsequent reports, psittacosis may be the cause of one percent of cases among community-acquired pneumonia[ 3 ]. Clinical manifestations of psittacosis vary from asymptomatic infection to severe systemic symptoms and may even lead to fatal systemic illness.…”

Section: Introductionmentioning

confidence: 99%

Co-infection of Chlamydia psittaci and Tropheryma whipplei: A case report

Du,

Chen

2023

World J Clin Cases

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Time series analysis is a valuable tool in epidemiology that complements the classical epidemiological models in two different ways: Prediction and forecast. Prediction is related to explaining past and current data based on various internal and external influences that may or may not have a causative role. Forecasting is an exploration of the possible future values based on the predictive ability of the model and hypothesized future values of the external and/or internal influences. The time series analysis approach has the advantage of being easier to use (in the cases of more straightforward and linear models such as Auto-Regressive Integrated Moving Average). Still, it is limited in forecasting time, unlike the classical models such as Susceptible-Exposed-Infectious-Removed. Its applicability in forecasting comes from its better accuracy for short-term prediction. In its basic form, it does not assume much theoretical knowledge of the mechanisms of spreading and mutating pathogens or the reaction of people and regulatory structures (governments, companies, etc. ). Instead, it estimates from the data directly. Its predictive ability allows testing hypotheses for different factors that positively or negatively contribute to the pandemic spread; be it school closures, emerging variants, etc. It can be used in mortality or hospital risk estimation from new cases, seroprevalence studies, assessing properties of emerging variants, and estimating excess mortality and its relationship with a pandemic.

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Psittacosis Pneumonia Features, Distinguishing Characteristics, and Outcomes: A Retrospective Study

Lu,

Gai,

et al. 2024

IDR

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Purpose Psittacosis is an often-neglected cause of community acquired pneumonia (CAP). The limited diagnostic methods for psittacosis pneumonia invariably result in an unfavourable prognosis. Consequently, the early detection of psittacosis pneumonia is crucial. This study aimed to analyse the characteristics, clinical features and treatments of the patients to improve early diagnosis and outcomes. Patients and Methods We retrospectively analyzed the clinical features and outcomes of 52 cases of psittacosis pneumonia diagnosed with next-generation sequencing (NGS) from January 2022 to August 2024 in a local tertiary hospital in China. Results Of the 52 patients, 18 had a clear exposure to poultry or birds. The main clinical manifestations included fever (100%, 52/52), cough (75.0%, 39/52), fatigue (57.7%, 30/352), and dyspnea (36.5%, 19/52). Significant elevations in neutrophil counts (NEUT), C-reactive protein (CRP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), D-dimer, lactate dehydrogenase (LDH), creatine kinase (CK), interleukin-6 (IL-6) and interferon-γ (IFN-γ), as well as reductions in lymphocyte (LY) and albumin (ALB) were observed. The main chest computed tomography (CT) features were consolidated. Eight patients diagnosed with severe CAP (SCAP) exhibited higher NEUT, CRP, procalcitonin (PCT), blood urea nitrogen (BUN), creatinine, D-Dimer and IL-6 levels, as well as lower oxygen index. The interval between the onset of symptoms and diagnosis was 6–34 days. C. psittaci infection was identified by metagenomic NGS (mNGS) or targeted NGS (tNGS) in all cases, and the average length of hospital stay for these patients was 9.4 days. Following the identification of the aetiology, all patients were promptly initiated on tetracycline- or fluoroquinolone-based therapy, with complete recovery observed in all cases. Conclusion Patients exposed to poultry should be alert to Chlamydia psittaci pneumonia. The application of NGS has improved the diagnostic accuracy of C. psittaci pneumonia, reduced unnecessary use of antibiotics, and shortened the course of disease. Patients who received tetracycline-based therapy showed a good prognosis.

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Importance of clinical history in the diagnosis of psittacosis: A case report

Cited by 3 publications

References 16 publications

Pneumonia Caused by Chlamydia psittaci and SARS-CoV-2 Coinfection Diagnosed Using Metagenomic Next-Generation Sequencing: A Case Report

Pneumonia Caused by Chlamydia psittaci and SARS-CoV-2 Coinfection Diagnosed Using Metagenomic Next-Generation Sequencing: A Case Report

Co-infection of Chlamydia psittaci and Tropheryma whipplei: A case report

Psittacosis Pneumonia Features, Distinguishing Characteristics, and Outcomes: A Retrospective Study

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