Importance of initial stress for abdominal aortic aneurysm wall motion: Dynamic MRI validated finite element analysis

Merkx, Mag Maarten; Veer, van 't Marcel Marcel; Speelman, Lambert; Breeuwer, Marcel; Buth, Jaap; Vosse, van de Fn Frans

doi:10.1016/j.jbiomech.2009.06.053

Cited by 29 publications

(20 citation statements)

References 20 publications

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“…In the recent paper of Merkx et al (2009), the wall displacements on the aneurysmatic abdominal aorta obtained via dynamic MRI and those computed via the FEM were compared.…”

Section: Resultsmentioning

confidence: 99%

Coupled fluid–structure interaction hemodynamics in a zero-pressure state corrected arterial geometry

Vavourakis

Papaharilaou

Ekaterinaris

2011

Journal of Biomechanics

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“…In the recent paper of Merkx et al (2009), the wall displacements on the aneurysmatic abdominal aorta obtained via dynamic MRI and those computed via the FEM were compared.…”

Section: Resultsmentioning

confidence: 99%

Coupled fluid–structure interaction hemodynamics in a zero-pressure state corrected arterial geometry

Vavourakis

Papaharilaou

Ekaterinaris

2011

Journal of Biomechanics

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“…As reported in [21], it is necessary for accurate AAA biomechanical modeling to recover the zero-pressure state configuration of the vessel wall, in order to improve wall distensibility estimation. A similar observation was made in the FSI analysis presented in [36], where both vessel wall deformation and blood flow characteristics were affected when the measured and not the zero-pressure state geometry of a carotid bifurcation was used in the FSI analysis.…”

Section: Finite Element Analysis Solvermentioning

confidence: 99%

The influence of intraluminal thrombus on noninvasive abdominal aortic aneurysm wall distensibility measurement

Metaxa

Kontopodis

Vavourakis

et al. 2014

Med Biol Eng Comput

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Abdominal aortic aneurysm wall distensibility can be estimated by measuring pulse pressure and the corresponding sac volume change, which can be obtained by measuring wall displacement. This approach, however, may introduce error if the role of thrombus in assisting the wall in bearing the pulse pressure loading is neglected. Our aim was to introduce a methodology for evaluating and potentially correcting this error in estimating distensibility. Electrocardiogram-gated computed tomography images of eleven patients were obtained, and the volume change between diastole and systole was measured. Using finite element procedures, we determined the equivalent pulse pressure loading that should be applied to the wall of a model where thrombus was digitally removed, to yield the same sac volumetric increase caused by applying the luminal pulse pressure to the model with thrombus. The equivalent instead of the measured pulse pressure was used in the distensibility expression. For a relative volumetric thrombus deposition (V ILT) of 50 %, a 62 % distensibility underestimation resulted when thrombus role was neglected. A strong linear correlation was observed between distensibility underestimation and V ILT. To assess the potential value of noninvasive wall distensibility measurement in rupture risk stratification, the role of thrombus on wall loading should be further investigated.

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“…Therefore, for high numerical simulation accuracy, it is important for the analyst to incorporate into the biomechanical model all necessary information including any pre-stressing of the solid structure. For example, as reported by recent cardiovascular studies 25,38 directly incorporating the original scanned geometry of an artery/vein into fluid-structure interaction simulations can give inaccurate predictions of the haemodynamics and the vascular biomechanical response. In addition, for pure structural analysis of a blood vessel wall at the full physiological pressure load, incorrect wall distensibility and stress distributions will be predicted if erroneous initial unstressed conditions are assumed.…”

Section: Introductionmentioning

confidence: 99%

An Inverse Finite Element u/p-Formulation to Predict the Unloaded State of In Vivo Biological Soft Tissues

2015

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Physically realistic patient-specific biomechanical modelling is of paramount importance for many medical applications, where the geometry of tissues or organs is usually constructed from in vivo images. However, it is common for such biological structures to correspond to a deformed state due to being under external loadings. This necessitates the determination of the stress distribution of the known deformed state through an inverse analysis approach. To achieve this, we propose here a generalised finite element displacement/pressure (u/p)-formulation for evaluating the unloaded configuration of in vivo biological soft tissues that exhibit quasi-incompressible behaviour under finite deformations. Validity and applicability of the proposed numerical framework to practical inverse analysis problems in biomechanics is demonstrated through various numerical examples. The corresponding simulations utilise in vivo measurements of patient-specific geometries derived from different medical imaging modalities, and include recovery of the pressure-free configuration of human aortas and the gravity-free shape of the female breast.

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Importance of initial stress for abdominal aortic aneurysm wall motion: Dynamic MRI validated finite element analysis

Cited by 29 publications

References 20 publications

Coupled fluid–structure interaction hemodynamics in a zero-pressure state corrected arterial geometry

Coupled fluid–structure interaction hemodynamics in a zero-pressure state corrected arterial geometry

The influence of intraluminal thrombus on noninvasive abdominal aortic aneurysm wall distensibility measurement

An Inverse Finite Element u/p-Formulation to Predict the Unloaded State of In Vivo Biological Soft Tissues

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