Imprint cytology from ultrasound-guided core biopsies: accurate and immediate diagnosis in a one-stop breast clinic

Jones, Lyn; Lott, M.; Calder, Caroline; Kutt, E.

doi:10.1016/j.crad.2004.02.016

Cited by 23 publications

(15 citation statements)

References 10 publications

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“…These values are comparable to some of the studies in the literature and are even better than some (table 5) [6,7,8,9,10,11,12,13,14,15,16]. It should be pointed out here that biopsy diagnosis is attained after immunohistochemistry which was not possible on cytology.…”

Section: Discussionsupporting

confidence: 70%

“…Our data clearly show that the results of ROSAC obtained by the cytotechnologist are equivalent to or better than most of the studies in the literature [9,10,12,13], besides being very cost-effective.…”

Section: Discussionmentioning

confidence: 48%

“…In most of the studies, imprint cytology is used as a technique for on-site adequacy checking with an adequacy rate in the range of 94-98% (table 5) [6,7,8,9,10,11,12,13,14,15,16]. …”

Section: Discussionmentioning

confidence: 99%

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The Role of Squash Cytology in Rapid On-Site Adequacy Checking and Rapid Diagnosis in Image-Guided Gun Biopsy at a Tertiary Cancer Center

Kane¹,

Prabhudesai²,

Ojha³

et al. 2013

Acta Cytologica

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Objective: To evaluate the role of squash cytology in rapid on-site adequacy checking (ROSAC) of image-guided gun biopsy and to determine its diagnostic accuracy at a tertiary cancer center. Study Design: This was a prospective study on 183 patients undergoing image-guided biopsy. Squash smears were prepared from biopsy cores and checked for adequacy by cytotechnologists. When adequate, more cores were sampled from the same area for histopathology. If inadequate, the procedure was repeated at the same sitting on a different area. The squash smears were reported by cytopathologists within 4 h after staining with conventional Papanicoloau stain. The results were compared with the final histopathology report. Results: The sampling was representative in 95.6% cases with concordance for adequacy in 97.3% cases. The sensitivity, specificity, positive predictive value and negative predictive value of squash cytology for diagnosis of the lesion were 99.4, 92.7, 97.7 and 97.4%, respectively. Conclusions: Squash cytology is an ideal and cost-effective technique for ROSAC of image-guided biopsies, which ensures adequacy, avoids repeat procedures and prevents delay in diagnosis. It can be effectively performed by trained cytotechnologists in radiology clinics. Squash cytology is also a cost-effective tool offering rapid diagnosis which expedites planning of treatment.

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Section: Discussionsupporting

confidence: 70%

Section: Discussionmentioning

confidence: 48%

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The Role of Squash Cytology in Rapid On-Site Adequacy Checking and Rapid Diagnosis in Image-Guided Gun Biopsy at a Tertiary Cancer Center

Kane¹,

Prabhudesai²,

Ojha³

et al. 2013

Acta Cytologica

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“…[85,87] Conversely, the other studies only correlated TI cytology diagnoses to the later CNB diagnoses (a surrogate gold standard assessment). As CNB can miss cancers and falsely diagnose non-malignant lesions as malignant (Figure 1), the true conclusiveness of TI cytology may have been under-or overestimated in these studies.…”

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 99%

“…[80][81][82][83][84][85][86][87][88][89] Unfortunately, only 2 studies used the final M A N U S C R I P T…”

Section: Combining Cytology and Histology In Preoperative Work-upmentioning

confidence: 99%

Preoperative cytological and histological diagnosis of breast lesions: A critical review

Kooistra

Wauters

Strobbe

et al. 2010

European Journal of Surgical Oncology (EJSO)

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Statement of expertiseThe first author, BK, has recently published several papers on fine needle aspiration, core needle biopsy and nipple discharge cytology. CW is an experienced pathologist and cytopathologist with special scientific interest in the position the diagnostic pathology in preoperative work-up of breast lesions. LS is a breast surgeon with special interest in preoperative work-up and has supervised several research projects on this subject in the past years. The senior author, TW, is an experienced professor in surgical oncology with special interest in diagnosis and surgical treatment of breast pathology. Key wordsBreast pathology; fine needle aspiration; core needle biopsy; core wash cytology; touch imprint cytology; breast surgery.

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Core imprint cytology of screen-detected breast lesions is predictive of the histologic results

Farshid¹,

Pieterse²

2006

Cancer

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Objective To study antibody‐independent contributions of B cells to inflammatory disease activity, and the immune consequences of B‐cell depletion with rituximab, in patients with multiple sclerosis (MS). Methods B‐Cell effector‐cytokine responses were compared between MS patients and matched controls using a 3‐signal model of activation. The effects of B‐cell depletion on Th1/Th17 CD4 and CD8 T‐cell responses in MS patients were assessed both ex vivo and in vivo, together with pharmacokinetic/pharmacodynamic studies as part of 2 rituximab clinical trials in relapsing–remitting MS. Results B Cells of MS patients exhibited aberrant proinflammatory cytokine responses, including increased lymphotoxin (LT):interleukin‐10 ratios and exaggerated LT and tumor necrosis factor (TNF)‐α secretion, when activated in the context of the pathogen‐associated TLR9‐ligand CpG‐DNA, or the Th1 cytokine interferon‐γ, respectively. B‐Cell depletion, both ex vivo and in vivo, resulted in significantly diminished proinflammatory (Th1 and Th17) responses of both CD4 and CD8 T cells. Soluble products from activated B cells of untreated MS patients reconstituted the diminished T‐cell responses observed following in vivo B‐cell depletion in the same patients, and this effect appeared to be largely mediated by B‐cell LT and TNFα. Interpretation We propose that episodic triggering of abnormal B‐cell cytokine responses mediates ‘bystander activation’ of disease‐relevant proinflammatory T cells, resulting in new relapsing MS disease activity. Our findings point to a plausible mechanism for the long‐recognized association between infections and new MS relapses, and provide novel insights into B‐cell roles in both health and disease, and into mechanisms contributing to therapeutic effects of B‐cell depletion in human autoimmune diseases, including MS. ANN NEUROL 2010;67:452–461

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Imprint cytology from ultrasound-guided core biopsies: accurate and immediate diagnosis in a one-stop breast clinic

Cited by 23 publications

References 10 publications

The Role of Squash Cytology in Rapid On-Site Adequacy Checking and Rapid Diagnosis in Image-Guided Gun Biopsy at a Tertiary Cancer Center

The Role of Squash Cytology in Rapid On-Site Adequacy Checking and Rapid Diagnosis in Image-Guided Gun Biopsy at a Tertiary Cancer Center

Preoperative cytological and histological diagnosis of breast lesions: A critical review

Core imprint cytology of screen-detected breast lesions is predictive of the histologic results

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