This chapter explores the synergies between facial profiling, machine learning, and emotion detection, revealing their impact on human psychology. It details the meticulous process of facial profiling and its applications in marketing, security, and human-computer interaction. The symbiotic relationship with machine learning advances facial recognition, sentiment analysis, and predictive applications. Emotion detection, a subset, finds diverse applications from mental health to virtual reality. The methodology stresses data quality and ethical considerations. The chapter serves as a beacon for researchers and practitioners, navigating the responsible integration of technology into psychology.