Improved Diagnosis of Low Intensity Spirocerca Lupi Infection by the Sugar Flotation Method

Markovics, A.; Medinski, B.

doi:10.1177/104063879600800326

Cited by 46 publications

(26 citation statements)

References 2 publications

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“…Flotation with sodium nitrate solution with an SG of 1.36 or supersaturated 33% zinc sulphate will concentrate the eggs. Improved diagnostic sensitivity has been shown with a modified sugar flotation technique (Markovics and Medinski, 1996). It is important to repeat a negative faecal flotation to improve diagnostic accuracy.…”

Section: Diagnosis Faecal Flotationmentioning

confidence: 99%

Spirocerca lupi infection in the dog: A review

Merwe

Kirberger

Clift

et al. 2008

The Veterinary Journal

161

191

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Spirocercosis is a disease occurring predominantly in Canidae, caused by the nematode Spirocerca lupi. Typical clinical signs are regurgitation, vomiting and dyspnoea. The lifecycle involves an intermediate (coprophagous beetle) and a variety of paratenic hosts. Larvae follow a specific migratory route, penetrating the gastric mucosa of the host, migrating along arteries, maturing in the thoracic aorta before eventually moving to the caudal oesophagus. Here the worm lives in nodules and passes larvated eggs which can be detected using zinc sulphate faecal flotation. Histologically, the mature oesophageal nodule is composed mostly of actively dividing fibroblasts.Spirocerca lupi-associated oesophageal sarcomas may occur and damage to the aorta results in aneurysms. A pathognomonic lesion for spirocercosis is spondylitis of the thoracic vertebrae. Primary radiological lesions include an oesophageal mass, usually in the terminal oesophagus, spondylitis, and undulation of the aortic border. Contrast radiography and computed tomography are helpful additional emerging modalities. Oesophageal endoscopy has a greater diagnostic sensitivity than radiography. Endoscopic biopsies are not sensitive for detecting neoplastic transformation. Doramectin is the current drug of choice, effectively killing adult worms and decreasing egg shedding. Early diagnosis of infection is still a challenge and to date no ideal regimen for prophylaxis has been published.

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Section: Diagnosis Faecal Flotationmentioning

confidence: 99%

Spirocerca lupi infection in the dog: A review

Merwe

Kirberger

Clift

et al. 2008

The Veterinary Journal

161

191

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“…For flotation, each sample (50 g) was centrifuged at 12,000 3 G for 15 min and subjected to flotation saturated with MgSO 4 for 30 min (Markovics and Medinski, 1996). Based on the morphologic characteristics (Sprent, 1968), B. schroederi-positive samples were identified and differentiated under light microscopy.…”

mentioning

confidence: 99%

Molecular Diagnosis ofBaylisascaris schroederiInfections in Giant Panda (Ailuropoda melanoleuca) Feces Using PCR

Zhou

Wang

et al. 2013

Journal of Wildlife Diseases

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“…Clinical signs, in endemic areas include vomiting or regurgitation, dysphagia, dyspnoea, pyrexia and anorexia (Bailey, 1972;Jubb et al, 1993;Lobetti, 2000). Definitive diagnosis is made by detection of typical embryonated eggs in fecal smears (Markovics and Medinski, 1996), and/or finding the parasite in the granulomatous lesions (Fox et al, 1988).…”

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confidence: 99%

Spirocercosis and its complications in stray dogs in Shiraz, southern Iran

Oryan¹,

Sadjjadi²,

Mehrabani³

et al. 2008

Vet. Med.

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Spirocerca lupi is accepted in Veterinary Medicine as the cause of true malignancies in dogs. Aortic lesions and esophageal nodular granulomas are pathological lesions of spirocercosis that are considered to be pathognomic for this disease. Post mortem and histopathological studies of 105 stray dogs both male and female of different age groups from various residential areas were performed and their esophagus were examined for any lesions and helminthic parasites. Twenty dogs (19.04%) were infected with S. lupi. The infection rate was significantly higher in dogs greater than one year old (23.5%) and in western areas (36.4%) with similar prevalence rate in males and females. At histopathologic level, two isolate but closely related fibrosarcoma masses were situated at the distal portion of the thoracic esophagus of one dog and in the site of junction of esophagus and stomach of another one. Metastasis were observed in the lung and mediastinal lymph nodes of one of the dogs. Despite presence of large population of stray dogs little information is available about S. lupi in this country, so this study was undertaken to obtain an overall picture of this infection in stray dogs of Shiraz area, southern Iran.

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Improved Diagnosis of Low Intensity Spirocerca Lupi Infection by the Sugar Flotation Method

Cited by 46 publications

References 2 publications

Spirocerca lupi infection in the dog: A review

Spirocerca lupi infection in the dog: A review

Molecular Diagnosis ofBaylisascaris schroederiInfections in Giant Panda (Ailuropoda melanoleuca) Feces Using PCR

Spirocercosis and its complications in stray dogs in Shiraz, southern Iran

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