Improved liquid chromatography tandem mass spectrometry method for the determination of phenolic compounds in virgin olive oil

Assessing the bioavailability of polyphenols and antioxidant properties of extra virgin argan oil by simulated digestion and Caco-2 cell assays. Comparative study with extra virgin olive oil

“…All the major olive oil phenols show good stability in the gastric phase of digestion, although very low levels of stability when exposed to small-intestine conditions (Soler et al, 2010). Therefore, the different phenolic composition of EVA and EVO (Charrouf & Guillaume, 2007;Suárez, Macià, Romero, & Moltiva, 2008) seems to determine the different behavior of the phenolic fraction under conditions of the digestive process (Dinnella et al, 2007). Moreover, around 11% of the total phenols recovered after digestion of EVA were detected in the residual fraction, i.e., they were not available to be absorbed in the small intestine, versus only 2.82% in EVO (P < 0.0001) ( Fig.…”

Impact of olive oil phenolic concentration on human plasmatic phenolic metabolites

“…Results are expressed as milligrammes of caffeic acid per kilogramme of olive oil. Subsequently, the phenolic composition of the three prepared FVOOs was analysed by HPLC coupled to tandem MS (MS/ MS) (Suárez, Macià, Romero & Motilva, 2008).…”

Digestion stability and evaluation of the metabolism and transport of olive oil phenols in the human small-intestinal epithelial Caco-2/TC7 cell line

“…The analyses were performed by UPLC-PDA-MS, as described by Suá rez et al (2008). Ionisation was achieved using an electrospray (ESI) interface operating in the negative mode [MÀH] À .…”