Improved oxidative biostability of porous shape memory polymers by substituting triethanolamine for glycerol

Weems, Andrew C.; Wacker, Kevin T.; Maitland, Duncan J.

doi:10.1002/app.47857

Cited by 11 publications

(10 citation statements)

References 48 publications

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“…The displayed strains at break are relatively large for highly crosslinked thermosetting materials, particularly for the limonene system after post-curing at high temperatures. 34,36,37 Strain at break was found to correlate with the post-polymerisation post-cure temperature (ESI Fig. S17 †), with limonene displaying approximately 180% strain before break after post-curing at 120°C (after irradiation), but after a 30°C post-curing step of the same duration, fracture strain was only 77.3% (55.9% strain for the prepolymer) ( Fig.…”

Section: Thermomechanical Testingmentioning

confidence: 99%

Terpene- and terpenoid-based polymeric resins for stereolithography 3D printing

et al. 2019

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Section: Thermomechanical Testingmentioning

confidence: 99%

Terpene- and terpenoid-based polymeric resins for stereolithography 3D printing

et al. 2019

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“…To increase the biodegradability of SMP foams, ester linkages were introduced onto foaming triols, triethanolamine (TEA), and glycerol (Gly), that have been previously used to fabricate SMP networks with good thermal properties (Singhal, Rodriguez, et al, 2012;Weems, Wacker, & Maitland, 2019). Chlorotrimethylsilane (3 mol.…”

Section: Esterification Of Triolsmentioning

confidence: 99%

Biodegradable shape memory polymer foams with appropriate thermal properties for hemostatic applications

Jang

Fletcher

Monroe

et al. 2020

J Biomedical Materials Res

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Shape memory polymer (SMP) foams are a promising material for hemostatic dressings due to their biocompatibility, high surface area, excellent shape recovery, and ability to quickly initiate blood clotting. Biodegradable SMP foams could eliminate the need for a secondary removal procedure of hemostatic material from the patients’ wound, further facilitating wound healing. In this study, we developed hydrolytically and oxidatively biodegradable SMP foams by reacting polyols (triethanolamine or glycerol) with 6‐aminocaproic acid or glycine to generate foaming monomers with degradable ester bonds. These monomers were used in foam synthesis to provide highly crosslinked SMP foam structures. The ester‐containing foams showed clinically relevant thermal properties that were comparable to controls and excellent shape recovery within eight min. Triethanolamine‐based ester‐containing foams showed interconnected porous structure along with increased mechanical strength. Faster hydrolytic and oxidative biodegradation rates were achieved in ester‐containing foams in comparison to controls. These biodegradable SMP foams with clinically applicable thermal properties possess great potential as an effective hemostatic device for use in hospitals or on battlefields.

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“…Previous work with polyurethane-based SMP foams has demonstrated a range of strain recoveries, ranging from complete recovery (coupled with a thermo-solvation swelling effect) to less than 10% strain. 7,8,31,33 The residual presence of alcohols in aliphatic polyurethane systems has been hypothesized to induce excess tackiness and reduce strain, and therefore volumetric, recovery. 33 The shape memory response of the foam was also examined to determine if pore orientation impacted the response (without solvent-induced swelling) by compressing sections along the foaming axis (z-axis), as well as in the xy-plane.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

Shape Memory Poly(β-hydroxythioether) Foams for Oil Remediation in Aquatic Environments

King

Constant

Weems

2021

ACS Appl. Mater. Interfaces

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Shape memory poly(β-hydroxythioether) foams were produced using organobase catalyzed reactions between epoxide and thiol monomers, allowing for the rapid formation of porous media within approximately 5 min, confirmed using both rheology and physical foam blowing. The porous materials possess ultralow densities (0.022 g × cm–3) and gel fractions of approximately 93%. Thermomechanical characterizations of the materials revealed glass transition temperatures tunable from approximately 50 to 100 °C, elastic moduli of approximately 2 kPa, and complete strain recovery upon heating of the sample above its glass transition temperature. The foams were characterized for their ability to take up oil from an aqueous multilayered ideal environment, revealing more than 2000% mass of oil (relative to the foam mass) could be collected. Importantly, while post-fabrication functionalization was possible with isocyanate chemistry followed by addition of hexadecanethiol or 3,3-bis(hexadecylthio)propan-1-ol, the oil collection efficiency of the system was not significantly enhanced, indicating that these materials, as porous media, possess unique attributes that make them appealing for environmental remediation without the need for costly modifications or manipulations.

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Improved oxidative biostability of porous shape memory polymers by substituting triethanolamine for glycerol

Abstract: The cover image was adapted from the work of Dr. Maitland and shows shape memory polymer foam. In this study, oxidative degradation rates of aliphatic shape memory polymer polyurethanes can be significantly reduced by substituting glycerol for polyols containing tertiary amines.

Cited by 11 publications

References 48 publications

Terpene- and terpenoid-based polymeric resins for stereolithography 3D printing

Terpene- and terpenoid-based polymeric resins for stereolithography 3D printing

Biodegradable shape memory polymer foams with appropriate thermal properties for hemostatic applications

Shape Memory Poly(β-hydroxythioether) Foams for Oil Remediation in Aquatic Environments

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