Improvement in mechanical and biological performance of porous baghdadite scaffold by applying chitosan coating

Soureshjani, Fatemeh Abbasi; Nilforoushan, Mohammad Reza; Sharifi, Hassan; Arefpour, Ahmadreza; Doostmohammadi, Ali

doi:10.1007/s00339-021-04475-z

Cited by 8 publications

(1 citation statement)

References 29 publications

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“…As a result of its exceptional biological properties, baghdadite ceramic (as filler, matrix, and coating) is at the center of extensive research in the biomedical materials field. This ceramic has shown an emerging area of biocomposite materials research due to its remarkable properties [ 27 , 30 , 38 , [45] , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] , [54] ]. The following sections will discuss the latest biomedical applications of baghdadite ceramics, the process of bioactivity mechanisms, and their behavior in vitro and in vivo conditions.…”

Section: Pure Baghdadite Ceramicmentioning

confidence: 99%

Recent advances on bioactive baghdadite ceramic for bone tissue engineering applications: 20 years of research and innovation (a review)

Sadeghzade

Liu²,

Wang³

et al. 2022

Materials Today Bio

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Section: Pure Baghdadite Ceramicmentioning

confidence: 99%

Recent advances on bioactive baghdadite ceramic for bone tissue engineering applications: 20 years of research and innovation (a review)

Sadeghzade

Liu²,

Wang³

et al. 2022

Materials Today Bio

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Nano hydroxyapatite architectonics to control the morphological, mechanical, and rheological properties of CH-rfGO-HA scaffolds for bone tissue

Mohammadzadeh,

Jafari,

Soltani

2024

Appl. Phys. A

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Development of 3D-Printed PCL/ Baghdadite Nanocomposite Scaffolds for Bone Tissue Engineering Applications

Emadi,

Baghani,

Khodaei

et al. 2024

J Polym Environ

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A signi cant obstacle in bone tissue engineering is the creation of biodegradable bone replacements with the requisite mechanical and biological capabilities to treat more severe and intricately shaped injuries.Baghdadite has recently indicated that active biological ions such as silicon (Si 4+ ) and zirconium (Zr 4+ ) have been proven to increase bone growth considerably. In this study, we produced 3D-printed PCL-based scaffolds containing different amounts of Baghdadite using the robocasting solvent technique. Notably, PCL with 40 and 60 wt.% Baghdadite scaffolds (PB40 and PB60) promoted a more biomimetic environment for in vitro bone growth as their proper bioactivity and cell viability results were obtained without the addition of osteoinductive components. The printing process produced 3D scaffolds with a compressive strength of 7.94 MPa and elastic modulus of 29.95 MPa in PB40. According to the analytical prediction models in PB40, the elastic modulus was 24.7 and 26.89 MPa. Also, adding 60 wt.% Baghdadite increased the degradation rate to 5.1% in two months, more than six times that of PCL-based scaffolds. Cell proliferation assay demonstrated that the optical density of MG63 cells after 7 days of culture increased from 1.43 ± 0.03 to 1.82 ± 0.20 in PB40 as compared to pure PCL scaffold. Furthermore, bioactivity evaluation, ion release assessment, and morphological observation results further revealed that incorporating Baghdadite into a 3D-printed PCL-based scaffold could improve bone regeneration.Our ndings demonstrate that the PCL/Baghdadite composite scaffold may be e ciently manufactured using 3D-printing technology and is extremely promising for bone tissue engineering applications.

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Improvement in mechanical and biological performance of porous baghdadite scaffold by applying chitosan coating

Cited by 8 publications

References 29 publications

Recent advances on bioactive baghdadite ceramic for bone tissue engineering applications: 20 years of research and innovation (a review)

Recent advances on bioactive baghdadite ceramic for bone tissue engineering applications: 20 years of research and innovation (a review)

Nano hydroxyapatite architectonics to control the morphological, mechanical, and rheological properties of CH-rfGO-HA scaffolds for bone tissue

Development of 3D-Printed PCL/ Baghdadite Nanocomposite Scaffolds for Bone Tissue Engineering Applications

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