This study presents the performance simulation of the R463A that has been developed to be retrofitted to replace the R404A. The R463A is primarily composed of hydrofluorocarbons/hydrocarbon/carbon dioxide (HFCs/HCs/CO2). The R463A refrigerant (GWP=1494) is a non azeotropic mixture of R32 (36%), R125 (30%), R134a (14%), R1234yf (14%), and R744 (6%). It is composed of polyol ester oil (POE), and classified as a Class A1 incombustible and non-toxic refrigerant. The R463A has a higher cooling capacity (Qe) than the R404A, as it is composed of hydrofluorocarbons (HFCs) R32 and carbon dioxide (CO2) R744, and also has a lower global warming potential (GWP) than the R404A due to the hydrofluoroolefins (HFOs) by R1234yf. The properties of the R463A and R404A that uses the REFPROP and CYCLE_D-HX software, is in accordance to the CAN/ANSI/AHRI540 standard airconditioning , heating, and refrigeration institute (AHRI). The normal boiling point of the R463A was found to be higher than the R404A by 23%, with a higher cooling capacity and a lower GWP value by 63% than the R404A. The critical pressure and temperature of the R463A was found to be higher than the R404A, i.e. it can be used in a high ambient temperature environment, and emits a higher refrigerant effect and heat reject with a lower global warming potential (GWP) than the R404A by 52%, due to its hydrofluoroolefins (HFOs) by R1234yf component. The COP of the R463A was found to be higher than the R404A by 10% under low temperature application.