Improvement of Nutritional Status among Tuberculosis Patients by <i>Channa striata</i> Supplementation: A True Experimental Study in Indonesia

Ma’rufi, Isa; Ali, Khaidar; Jati, Sigit Kusuma; Sukmawati, Anik; Ardiansyah, Kurnia; Ningtyias, Farida Wahyu

doi:10.1155/2020/7491702

Cited by 7 publications

(10 citation statements)

References 41 publications

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“…The findings of Isa Ma’rufi et al . [ 29 ] also supported this finding, and their study showed that by taking the BMI supplements for a month, the patients with TB ascended faster than the control group and the disease improved with minimal negative effects of the disease. Therefore, to eliminate or reduce the incidence of TB in the community, further study on the use of dietary supplements in patients with TB is needed.…”

Section: Methodsmentioning

confidence: 84%

Different diets and their effect on tuberculosis prevention in HIV patients

Kouhpayeh

2022

Journal of Family Medicine and Primary Care

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Introduction: The relationship between nutrition and human immunodeficiency virus (HIV) infection, tuberculosis, and other infectious diseases is logically proven. Nutrition affects the immune system and the health of the organs. Inadequate dietary intake endangers the immune system, which itself increases susceptibility to disease and often culminates in active disease. The disease then reduces the body’s appetite and ability to absorb nutrients, and the cycle continues. Considering the importance of the role of nutrition in the health of acquired immune deficiency syndrome (AIDS) patients, this current review aimed to discuss the different diets and their effects on tuberculosis (TB) prevention in HIV patients. Method and Materials: The present study evaluates the important points related to AIDS and the prevention and treatment of this disease by considering the diet and known scientific cases during the last 10 years, in simple terms, the prevalence of this disease. Result: Articles were searched by valid databases in May 2021. The findings showed that in addition to malnutrition, the high prevalence of infectious diseases can have serious consequences for public health. Many people will be safe from getting infections if there are safe and effective interventions for many of these infectious diseases. Conclusion: Based on the information presented herein, it is clear that TB affects the nutritional status. Many patients with active TB experience severe weight loss, and many people with the symptoms show a lack of vitamins and minerals.

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Section: Methodsmentioning

confidence: 84%

Different diets and their effect on tuberculosis prevention in HIV patients

Kouhpayeh

2022

Journal of Family Medicine and Primary Care

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“…Thus, in order to combat this issue, vitamins and nutrient supplementations (e.g., Channa striata) have been utilized in Indonesia. This extract-containing supplementation was discovered to induce an improvement in BMI levels and accelerate recovery in TB patients (Ma'rufi et al, 2019;Ma'rufi et al, 2020). In Medan, vitamin A and C supplementations in TB patients were also discovered to improve sputum conversion, meaning that the previously TB-positive sputum has been converted to a TBnegative smear result (Safitri et al, 2022;Sari et al, 2019).…”

Section: Health Conditionsmentioning

confidence: 99%

Drug-Resistant Pulmonary Tuberculosis

Putri¹,

Salim²,

Gunawan³

et al. 2023

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Tuberculosis (TB) caused by the pathogenic bacteria Mycobacterium tuberculosis (MTb) still remains a highly prevalent disease, particularly in low and middle-income countries. Due to the bacteria’s atypical cell wall structure, ability to form granuloma, and capacity to switch between replicating and non-replicating states in the host lung parenchyma, the fundamental treatment of patients diagnosed with TB involves a 6-month long daily drug administration. With Indonesia ranking among the nations with the highest TB burden worldwide, there has been an alarming increase of drug-resistant MTb (DR-MTb) strains all over the country in recent years. However, there are currently limited studies available that highlight MTb resistance profiles across different regions within Indonesia. The major risk factors contributing to the emergence and spread of TB in Indonesia include health conditions, environmental conditions, and socioeconomic status. Furthermore, natural compounds and drug repurposing can be employed to combat the further spread of DR-MTb strains across the country, especially in rural regions.

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“…Many studies have been developed using this fish species. Snakehead extract supplementation in tuberculosis patients is known to significantly increase Body Mass Index (BMI) with minimal adverse effects (Ma'rufi et al, 2020). Furthermore, its fillet extract is known to exert a hepatoprotective effect in a rat model induced with oxidative stress (Suhartono et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Oral acute and subchronic (28-day) toxicity studies of snakehead fish (Channa striata)

Sasongko

2022

Indonesian J Pharm

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Food and drug control authorities in each country have issued warnings about the toxic effect potential of using commonly consumed traditional medicines. The safety assurance, standardization, and market regulation of herbal medicines being sold need to be determined. This study's goal is to investigate the acute and subchronic toxicity of cold-processed snakehead fish (Channa striata) flesh. In-vivo rats models were given dosages of 350, 1400, and 5600 mg/kg processed snakehead fish (SF) and were monitored for toxic symptoms and mortality for 14 days. Meanwhile, regarding subchronic toxicity, doses of 350, 700, and 1400 mg/kg SF were administered orally for 28 days. Afterward, the animal subjects were sacrificed for histopathological, hematological, and biochemical examinations. There were no evidence of toxicity or mortality in rats during the acute examination, which lasted 14 days. The subchronic toxicity results showed no significant changes in most of the hematological, biochemical, and histological profiles of the organs. Some changes observed in blood biochemistry and relative organ weight were assumed as a temporary effect and not a sign of toxicity. The overall results showed that the SF was non-toxic up to 1400 mg/kg, which can be considered a safe dose for the application of health supplement raw materials.

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Improvement of Nutritional Status among Tuberculosis Patients by Channa striata Supplementation: A True Experimental Study in Indonesia

Cited by 7 publications

References 41 publications

Different diets and their effect on tuberculosis prevention in HIV patients

Different diets and their effect on tuberculosis prevention in HIV patients

Drug-Resistant Pulmonary Tuberculosis

Oral acute and subchronic (28-day) toxicity studies of snakehead fish (Channa striata)

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