Improvement of restless legs syndrome and trichotillomania with aripiprazole

Virit, Osman; Selek, Salih; Savaş, Haluk A.; Kokacya, Hanifi

doi:10.1111/j.1365-2710.2009.01051.x

Cited by 17 publications

(16 citation statements)

References 14 publications

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“…No particular drug, with the exception of aripiprazole, was associated with a higher appearance of RLS. This drug has been related with both the production and the alleviation of RLS symptoms (McLean, 2004;Christensen et al, 2006;Virit et al, 2009). Antipsychotic use has been linked to a higher risk of developing RLS due to its capacity to result in dopamine depletion (Cohrs et al, 2008).…”

Section: Discussionmentioning

confidence: 98%

Prevalence and clinical correlates of restless legs syndrome among psychogeriatric patients

Agüera-Ortíz

Perez

Osorio

et al. 2011

Int J Geriat Psychiatry

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Section: Discussionmentioning

confidence: 98%

Prevalence and clinical correlates of restless legs syndrome among psychogeriatric patients

Agüera-Ortíz

Perez

Osorio

et al. 2011

Int J Geriat Psychiatry

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“…Recently, ARP has been reported to improve the TTM symptoms of adult patients [9, 10]. In addition, it has been reported that only 1.5 to 3.0 mg/day of ARP alone improved TTM symptoms in a 20-year-old man [11].…”

Section: Case Presentationmentioning

confidence: 99%

Treatment of puberty trichotillomania with low-dose aripiprazole

Sasaki

Iyo

2015

Ann Gen Psychiatry

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The present case is of a 14-year-old female with trichotillomania (TTM) that was treated with a low dose of aripiprazole (ARP) 1.5 mg/day. To our knowledge, this is the first published report to show an improvement of pubertal TTM using an ultra-low dose of ARP. In this case, a 50-mg fluvoxamine monotherapy for 2 years and a subsequent 4-month comprehensive cognitive behavioral therapy (CBT) monotherapy did not improve her hair-pulling symptoms. However, the treatment with a low-dose ARP of 1.5 mg/day dramatically improved her TTM symptoms without extrapyramidal symptoms. In this regard, low-dose ARP treatment for TTM might be a safe alternative to antidepressants, which carry the risk of agitation with suicidal ideation in adolescents.

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“…[125][126][127] There are case reports of improvement of RLS symptoms in patients taking the atypical antipsychotic aripiprazole, which has partial agonist and antagonist properties. [128][129][130] At present, there is no literature on RLS and electroconvulsive therapy for depression.…”

Section: Pharmacologic Treatment For Rlsmentioning

confidence: 99%

Mood Disorders in Restless Legs Syndrome (Willis-Ekbom Disease)

Becker¹,

Sharon²

2014

J. Clin. Psychiatry

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Study Selection: 173 publications were retrieved. Articles related to the association between idiopathic RLS and depression, anxiety, and mood disorders were reviewed. In total, 32 epidemiologic studies were identified. These studies were reviewed in detail and ranked according to quality.Data Extraction: Data were extracted on the basis of relevance to the topic. Epidemiologic studies were assessed using 3 parameters: methodology, data quality, and generalizability of the results. Each factor was scored from 1 (high quality) to 4 (low quality), giving a total score of between 3 and 12 for each study.Results and Conclusions: RLS and mood disorders are frequently comorbid. Recognition and appropriate treatment of comorbid RLS are particularly important in patients with psychiatric disorders, as RLS is a common medical reason for insomnia, and antidepressant use may exacerbate sensory symptoms.

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Improvement of restless legs syndrome and trichotillomania with aripiprazole

Cited by 17 publications

References 14 publications

Prevalence and clinical correlates of restless legs syndrome among psychogeriatric patients

Prevalence and clinical correlates of restless legs syndrome among psychogeriatric patients

Treatment of puberty trichotillomania with low-dose aripiprazole

Mood Disorders in Restless Legs Syndrome (Willis-Ekbom Disease)

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