Improvement of surface bioactivity on titanium by water and hydrogen plasma immersion ion implantation

Xie, Yi; Liu, Xuanyong; Huang, Anping; Ding, Chuanxian; Chu, Paul K.

doi:10.1016/j.biomaterials.2005.03.032

Cited by 105 publications

(57 citation statements)

References 31 publications

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“…Therefore, creating a bioactive surface for the TC is helpful to promote cell-material interactions and improve osseointegration of the implants [6,7]. Among various surface modification technologies, biochemical methods, by immobilizing the main components of the extracellular matrix (ECM), enzymes or peptides on biomaterials surfaces, have shown great potential to induce specific cell responses and reinforce the tissue-implant interface [8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Fabrication and in vitro evaluation of stable collagen/hyaluronic acid biomimetic multilayer on titanium coatings

Xie

Tan

et al. 2013

J. R. Soc. Interface.

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Layer-by-layer (LBL) self-assembly technique has been proved to be a highly effective method to immobilize the main components of the extracellular matrix such as collagen and hyaluronic acid on titanium-based implants and form a polyelectrolyte multilayer (PEM) film by electrostatic interaction. However, the formed PEM film is unstable in the physiological environment and affects the long-time effectiveness of PEM film. In this study, a modified LBL technology has been developed to fabricate a stable collagen/hyaluronic acid (Col/HA) PEM film on titanium coating (TC) by introducing covalent immobilization. Scanning electron microscopy, diffuse reflectance Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy were used to characterize the PEM film. Results of Sirius red staining demonstrated that the chemical stability of PEM film was greatly improved by covalent crosslinking. Cell culture assays further illustrated that the functions of human mesenchymal stem cells, such as attachment, spreading, proliferation and differentiation, were obviously enhanced by the covalently immobilized Col/ HA PEM on TCs compared with the absorbed Col/HA PEM. The improved stability and biological properties of the Col/HA PEM covalently immobilized TC may be beneficial to the early osseointegration of the implants.

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Section: Introductionmentioning

confidence: 99%

Fabrication and in vitro evaluation of stable collagen/hyaluronic acid biomimetic multilayer on titanium coatings

Xie

Tan

et al. 2013

J. R. Soc. Interface.

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“…The peak at 2360 cm -1 resulted from the adsorbed H2O molecules, which were not removed completely after sol-gel coating. The peaks at 1242 cm -1 , 1111 cm -1 , 1035 cm -1 and 860 cm -1 correspond to the vibration mode of Ti-OH [70,71].…”

Section: Ramanmentioning

confidence: 99%

Synthesis, Characterization and Properties of Zirconium Oxide (ZrO2)-Doped Titanium Oxide (TiO2) Thin Films Obtained via Sol-Gel Process

Bensaha¹,

Bensouyad²

2012

Heat Treatment - Conventional and Novel Applications

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“…Chu and coworkers [145][146][147] have undertaken an extensive amount of research into this field and have shown that it is possible to use plasma based surface modification to enhance the bioactivity of diamond-like carbon. From research such as this, it is possible to foresee that plasma-based technologies could potentially be used for polymeric biomaterials in order to improve upon their bioactivity for use in biological environments.…”

Section: Figure 7: Sem Images Of (A) As-received and (B) Plasma Surfamentioning

confidence: 99%

Surface Treatments to Modulate Bioadhesion: A Critical Review

Waugh¹,

Toccaceli²,

Gillett³

et al. 2016

rev adhes adhesives

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On account of the recent increase in importance of biological and microbiological adhesion in industries such as healthcare and food manufacturing many researchers are now turning to the study of materials, wettability and adhesion to develop the technology within these industries further. This is highly significant as the stem cell industry alone, for example, is currently worth £3.5 million in the United Kingdom (UK) alone. This paper reviews the current state-of-the-art techniques used for surface treatment with regards to modulating biological adhesion including laser surface treatment, plasma treatment, micro/nano printing and lithography, specifically highlighting areas of interest for further consideration by the scientific community. What is more, this review discusses the advantages and disadvantages of the current techniques enabling the assessment of the most attractive means for modulating biological adhesion, taking in to account cost effectiveness, complexity of equipment and capabilities for processing and analysis.

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Improvement of surface bioactivity on titanium by water and hydrogen plasma immersion ion implantation

Cited by 105 publications

References 31 publications

Fabrication and in vitro evaluation of stable collagen/hyaluronic acid biomimetic multilayer on titanium coatings

Fabrication and in vitro evaluation of stable collagen/hyaluronic acid biomimetic multilayer on titanium coatings

Synthesis, Characterization and Properties of Zirconium Oxide (ZrO2)-Doped Titanium Oxide (TiO2) Thin Films Obtained via Sol-Gel Process

Surface Treatments to Modulate Bioadhesion: A Critical Review

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