Improvement of the Stability and Mechanical Properties of Resorbable Phosphate Glasses by the Addition of TiO₂

A review of bioactive glasses: Their structure, properties, fabrication and apatite formation

“…Titania doped glass compositions based on the P 2 O 5 -CaO-Na 2 O-TiO 2 system have shown controlled solubility. 145,146 In addition to this, the chemical composition is close to the bone mineral phase. It further demonstrates that this glass has an advantage over polymeric scaffolds due to the fact that the glass can positively affect the material-cell interaction.…”

In situ thermal and structural characterization of bioactive calcium phosphate glass ceramics containing TiO2 and MgO oxides: High temperature – XRD studies

“…However, a balance between 0022 their degradation rate and the bone remodeling time must be considered, as some glass systems are too soluble for some purposes. It is well known that by modifying the composition of these glass ceramics, the degradation rate can be controlled, and this can be considerably reduced by the incorporation of some metallic oxides in the glass network, such as TiO 2 [1][2][3][4][5][6]. Previous reports of the preparation of glass and glass ceramics in the CaO-P 2 O 5 -TiO 2 system have indicated that biocompatible and bioactive phases may be produced [7,8].…”

Development of a Biodegradable Composite Scaffold for Bone Tissue Engineering: Physicochemical, Topographical, Mechanical, Degradation, and Biological Properties

“…Both CaO and TiO 2 enhance glass stability, particularly TiO 2 given its small ionic radius and the large charge on the Ti 4+ ion [18,19]. The characteristics of the Ti 4+ ion allow it to penetrate into the vitreous arrangement, inducing a higher degree of reticulation in the glass network.…”