Improving Fat Transfer Viability

Geissler, Palmyra; Davis, Kathryn E.; Roostaeian, Jason; Unger, Jacob G.; Huang, Jingjing; Rohrich, Rod J.

doi:10.1097/prs.0000000000000398

Cited by 89 publications

(32 citation statements)

References 20 publications

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“…[ 18 ] Novel strategies have thus been employed to enhance cytoprotection of the ASCs at the target site, which includes ischaemic preconditioning, pharmacological therapy, refinement of liposuction techniques to minimise trauma, as well as the addition of growth factors. [ 5 19 20 ] Future experimental work will be centred on safe and Food and Drug Administration - approved agents, which may be administered in conjunction with ASC transplantation to maximise the therapeutic efficacy at the target site.…”

Section: Clinical and Experimental Trialsmentioning

confidence: 99%

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Role of adipose-derived stem cells in fat grafting and reconstructive surgery

Tan¹,

Ng²,

Zhan³

et al. 2016

J Cutan Aesthet Surg

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Autologous fat grafting is commonly utilised to reconstruct soft tissue defects caused by ageing, trauma, chronic wounds and cancer resection. The benefits of fat grafting are minimal donor site morbidity and ease of availability through liposuction or lipectomy. Nonetheless, survival and longevity of fat grafts remain poor post-engraftment. Various methods to enhance fat graft survival are currently under investigation and its stem cell constituents are of particular interest. Cell-assisted lipotransfer refers to the addition of adipose-derived stem cell (ASC) rich component of stromal vascular fraction to lipoaspirate, the results of which have proven promising. This article aims to review the role of ASCs in fat grafting and reconstructive surgery.

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Section: Clinical and Experimental Trialsmentioning

confidence: 99%

“…have demonstrated that adipocyte viability was greater in the lower abdomen as compared to the flanks. [ 19 ]…”

Section: Isolation and Harvesting Of Adipose Stem Cellsmentioning

confidence: 99%

Role of adipose-derived stem cells in fat grafting and reconstructive surgery

Tan¹,

Ng²,

Zhan³

et al. 2016

J Cutan Aesthet Surg

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“…In addition to that our research's lack of data regarding patients' age, BMI, and estrogen status as increasing evidence seems to correlate these variables to clinical outcome [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

Autologous Fat Grafting Reduces Pain in Irradiated Breast: A Review of Our Experience

Caviggioli

Maione

Klinger

et al. 2015

Stem Cells International

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Introduction. Pain syndromes affect women after conservative and radical breast oncological procedures. Radiation therapy influences their development. We report autologous fat grafting therapeutical role in treating chronic pain in irradiated patients. Materials and Methods. From February 2006 to November 2014, we collect a total of 209 patients who meet the definition of “Postmastectomy Pain Syndrome” (PMPS) and had undergone mastectomy with axillary dissection (113 patients) or quadrantectomy (96 patients). Both procedures were followed by radiotherapy. We performed fat grafting following Coleman's procedure. Mean amount of adipose tissue injected was 52 cc (±8.9 cc) per breast. Seventy-eight in 209 patients were not treated surgically and were considered as control group. Data were gathered through preoperative and postoperative VAS questionnaires; analgesic drug intake was recorded. Results. The follow-up was at 12 months (range 11.7–13.5 months). In 120 treated patients we detected pain decrease (mean ± SD point reduction, 3.19 ± 2.86). Forty-eight in 59 patients stopped their analgesic drug therapy. Controls reported a mean ± SD decrease of pain of 1.14 ± 2.72. Results showed that pain decreased significantly in patients treated (p < 0.005, Wilcoxon rank-sum test). Conclusion. Our 8-year experience confirms fat grafting effectiveness in decreasing neuropathic pain.

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“…We chose the abdominal area as the donor site, as recommended in the recent literature. 5 We used the FAT WASHER system (Groupe SEBBIN, Boissy L’Aillerie, France), a closed system for washing and decanting fat, thus avoiding centrifugation. After infiltration of the donor area with Klein solution, a 3-mm accelerator-type cannula was used to harvest the fat with limited vacuum (0.4 atm).…”

Section: Case Reportmentioning

confidence: 99%

Scar Tissue Causing Saphenous Nerve Entrapment: Percutaneous Scar Release and Fat Grafting

Ulloa

Banda

2017

Plastic and Reconstructive Surgery - Global Open

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Summary:Painful neuropathies can be caused by nerve compression or neuromas. Nerve compressions can arise from scar adhesions causing painful posttraumatic entrapment of nerve branches via fibrosis. The classical treatment methods include neurolysis and nerve transposition. In this case, we present the treatment of recurrent scar entrapment of the saphenous nerve with percutaneous neurolysis and lipofilling in a patient who had previously undergone an open neurolysis procedure. Resolution of the condition without any complications was noted during the 2-month clinical follow-up. Percutaneous neurolysis and lipofilling are shown to be safe and reproducible methods for the treatment of neuropathic compressive scars.

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Improving Fat Transfer Viability

Abstract: Therapeutic, II.

Cited by 89 publications

References 20 publications

Role of adipose-derived stem cells in fat grafting and reconstructive surgery

Role of adipose-derived stem cells in fat grafting and reconstructive surgery

Autologous Fat Grafting Reduces Pain in Irradiated Breast: A Review of Our Experience

Scar Tissue Causing Saphenous Nerve Entrapment: Percutaneous Scar Release and Fat Grafting

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