Improving Health Outcomes for Youth Living With the Human Immunodeficiency Virus

Naar‐King, Sylvie; Parsons, Jeffrey T.; Murphy, Debra A.; Chen, Xinguang; Harris, D.R.; Belzer, Marvin

doi:10.1001/archpediatrics.2009.212

Cited by 75 publications

(48 citation statements)

References 34 publications

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“…Two other RCTs showed promising, if mixed, results (198, 199), whereas others demonstrated promising trends but had significant methodological limitations or did not achieve statistical significance (200, 201). …”

Section: Guidelinesmentioning

confidence: 98%

Guidelines for Improving Entry Into and Retention in Care and Antiretroviral Adherence for Persons With HIV: Evidence-Based Recommendations From an International Association of Physicians in AIDS Care Panel

Thompson¹,

Mugavero²,

Amico³

et al. 2012

Ann Intern Med

544

460

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Description After HIV diagnosis, timely entry into HIV medical care and retention in that care are essential to the provision of effective antiretroviral therapy (ART). ART adherence is among the key determinants of successful HIV treatment outcome and is essential to minimize the emergence of drug resistance. The International Association of Physicians in AIDS Care convened a panel to develop evidence-based recommendations to optimize entry into and retention in care and ART adherence for people with HIV. Methods A systematic literature search was conducted to produce an evidence base restricted to randomized, controlled trials and observational studies with comparators that had at least 1 measured biological or behavioral end point. A total of 325 studies met the criteria. Two reviewers independently extracted and coded data from each study using a standardized data extraction form. Panel members drafted recommendations based on the body of evidence for each method or intervention and then graded the overall quality of the body of evidence and the strength for each recommendation. Recommendations Recommendations are provided for monitoring of entry into and retention in care, interventions to improve entry and retention, and monitoring of and interventions to improve ART adherence. Recommendations cover ART strategies, adherence tools, education and counseling, and health system and service delivery interventions. In addition, they cover specific issues pertaining to pregnant women, incarcerated individuals, homeless and marginally housed individuals, and children and adolescents, as well as substance use and mental health disorders. Recommendations for future research in all areas are also provided.

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Section: Guidelinesmentioning

confidence: 98%

Guidelines for Improving Entry Into and Retention in Care and Antiretroviral Adherence for Persons With HIV: Evidence-Based Recommendations From an International Association of Physicians in AIDS Care Panel

Thompson¹,

Mugavero²,

Amico³

et al. 2012

Ann Intern Med

544

460

View full text Add to dashboard Cite

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“…This is consistent with previous work that has been done with both chronically ill children and with HIV patients. 23–24 …”

Section: Discussionmentioning

confidence: 99%

“…One study found that those who had received MI had lower viral loads than the control group after six months but this was not sustained at nine months. 23 The other study examined whether alcohol and marijuana use could be affected by the MI in a Healthy choices study. It found that alcohol use was reduced at 15 months in MI group as compared to the control group.…”

Section: Introductionmentioning

confidence: 99%

Effect of an Empowerment Intervention on Antiretroviral Drug Adherence in Thai Youth

Kaihin

Kasatpibal

Chitreechuer

et al. 2014

Behavioral Medicine

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A pilot study was conducted to determine effects of an empowerment intervention on antiretroviral therapy (ART) adherence among Thai youth living with HIV/AIDS. It compared two groups of 23 young persons (15–24 years) who receive ART from AIDS clinics at 2 community hospitals. One hospital’s patients served as the experimental group, and the other as a control group. The experimental groups attended five sessions that empowered them to take control of their own health. The control group received standard of care. The data were analyzed using descriptive statistics and Chi-square statistics. Before the empowerment, no one from the experimental group or the control group had ART adherence ≥95%. After the intervention, the 82.6% of the experimental group had ≥95% adherence compared to the control group, which had 21.7% adherence (p<.0001). The empowerment intervention resulted in a significant increase in ART adherence among Thai youth.

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“…We targeted only two behaviors because the original Healthy Choices focused on two of the most problematic of the three behaviors above for each participant (Naar-King et al, 2009). It is more feasible to address two instead of three behaviors in the four sessions.…”

Section: Methodsmentioning

confidence: 99%

“…We formerly demonstrated that an MI-based Healthy Choices intervention was effective in reducing sexual risk, alcohol use, and plasma HIV viral loads among HIV+ youth in the U.S. (Chen, Murphy, Naar-King, & Parsons, 2011; Murphy, Chen, Naar-King, & Parsons, 2012; Naar-King et al, 2009). Moreover, the Healthy Choices intervention was also associated with a significant reduction in depression in this population (Naar-King, Parsons, Murphy, Kolmodin, & Harris, 2010).…”

Section: Introductionmentioning

confidence: 99%

Motivational Interviewing Targeting Risky Sex in HIV-Positive Young Thai Men Who Have Sex with Men

et al. 2014

Self Cite

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Motivational interviewing (MI) has been shown to reduce sexual risks among HIV-positive men who have sex with men (HMSM) in the U.S. We conducted a randomized trial of Healthy Choices, a 4-session MI intervention, targeting sexual risks among 110 HIV-positive youth ages 16–25 years in Thailand. Risk assessments were conducted at baseline, 1 month, and 6 months post-intervention. This report presents the analysis of 74 HMSM in the study. There were 37 HMSM in the Intervention group and 37 in the control group. The proportions of participants having anal sex and having sex with either HIV-uninfected or unknown partners in past 30 days were significantly lower in Intervention group than in control group at 6 months post-intervention (38% vs. 65%, p = .04; and 27% vs. 62%, p < .01, respectively). There were no significant differences in general mental health scores and HIV stigma scores between the two groups at any study visit. Thirty-five (95%) HMSM in the Intervention group vs. 31 (84%) in control group attended ≥3 sessions. Loss to follow-up was 8% and 30%, respectively (p = .04). Healthy Choices for young Thai HMSM was associated with sexual risk reduction. Improvements in mental health and HIV stigma were noted in Intervention group. Healthy Choices is a promising behavioral intervention and should be further developed to serve the needs of young HMSM in resource-limited countries.

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Improving Health Outcomes for Youth Living With the Human Immunodeficiency Virus

Cited by 75 publications

References 34 publications

Guidelines for Improving Entry Into and Retention in Care and Antiretroviral Adherence for Persons With HIV: Evidence-Based Recommendations From an International Association of Physicians in AIDS Care Panel

Guidelines for Improving Entry Into and Retention in Care and Antiretroviral Adherence for Persons With HIV: Evidence-Based Recommendations From an International Association of Physicians in AIDS Care Panel

Effect of an Empowerment Intervention on Antiretroviral Drug Adherence in Thai Youth

Motivational Interviewing Targeting Risky Sex in HIV-Positive Young Thai Men Who Have Sex with Men

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