Improving Metabolic Control Through Functional Foods

Silva, João C. P.; Jones, John G.

doi:10.2174/0929867324666170523130123

Cited by 8 publications

(2 citation statements)

References 103 publications

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“…Chylomicrons and LDL remnants are catabolized in the liver. Changes in the plasma lipid spectrum are important risk factors for the development of cardiovascular diseases (54,2).…”

Section: U N C O R R E C T E Dmentioning

confidence: 99%

Obesity, elevated levels of fasting plasma glucose and type 2 diabetes are associated with aortic stiffness

KUPCOVA¹,

MURIN²,

WIMMEROVA³

et al. 2023

BLL

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OBJECTIVES: Obesity and metabolic syndrome (MetS) are associated with structural and functional vascular abnormalities. MetS and its components may increase arterial stiffness and the risk of cardiovascular events. However, the relationship of MetS and its components, including obesity, with arterial stiffness is still not fully understood. SUBJECTS AND METHODS: In a group of 116 patients undergoing treatment for hypertension, we searched for the relationships between parameters of MetS and aortic stiffness expressed by pulse wave velocity (PWVAo). PWVAo was measured using an arteriograph working on the oscillometric principle, and pulse wave analysis (PWA) for noninvasive assessment of the parameters of central hemodynamics. RESULTS: From the cluster of parameters of MetS we found a signifi cant association between body mass index (BMI) and aortic stiffness, and between fasting plasma glucose/type 2 diabetes (FPG/T2DM) and aortic stiffness. We did not fi nd signifi cant relationships between other components of MetS (HDL cholesterol and triglycerides) and aortic stiffness, based on the infl uence of hypolipidemic therapy. Arterial stiffness increased with age and was higher in females. CONCLUSION: Arterial stiffness was associated with age, sex, and MetS components (BMI and FPG/T2DM). Surprisingly, the parameters of dyslipidemia do not infl uence stiffness parameters, which can be explained by hypolipidemic therapy. The infl uence of hypolipidemic therapy should therefore be borne in mind when evaluating arterial tree function (Tab. 7, Ref. 62).

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“…Chylomicrons and LDL remnants are catabolized in the liver. Changes in the plasma lipid spectrum are important risk factors for the development of cardiovascular diseases (54,2).…”

Section: U N C O R R E C T E Dmentioning

confidence: 99%

Obesity, elevated levels of fasting plasma glucose and type 2 diabetes are associated with aortic stiffness

KUPCOVA¹,

MURIN²,

WIMMEROVA³

et al. 2023

BLL

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“…There is an increasing number of studies concerning how functional foods can improve or be supplemented as an auxiliary treatment in metabolic disorders, such as obesity, atherosclerosis or diabetes. Functional foods seem to have additional physiological benefits and contribute to the reduction of the risk of chronic diseases beyond their basic nutritional functions [ 111 , 112 ].…”

Section: Functional Foods and Diabetesmentioning

confidence: 99%

Maintaining Digestive Health in Diabetes: The Role of the Gut Microbiome and the Challenge of Functional Foods

et al. 2021

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Over the last decades, the incidence of diabetes has increased in developed countries and beyond the genetic impact, environmental factors, which can trigger the activation of the gut immune system, seem to affect the induction of the disease process. Since the composition of the gut microbiome might disturb the normal interaction with the immune system and contribute to altered immune responses, the restoration of normal microbiota composition constitutes a new target for the prevention and treatment of diabetes. Thus, the interaction of gut microbiome and diabetes, focusing on mechanisms connecting gut microbiota with the occurrence of the disorder, is discussed in the present review. Finally, the challenge of functional food diet on maintaining intestinal health and microbial flora diversity and functionality, as a potential tool for the onset inhibition and management of the disease, is highlighted by reporting key animal studies and clinical trials. Early onset of the disease in the oral cavity is an important factor for the incorporation of a functional food diet in daily routine.

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