This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. . QUARTZ performs well in terms of segmentation accuracy, calibre measurement, optic disc and arteriole/venule recognition. The system provides a rich quantification of retinal vessel morphology, which has potential medical applications in identifying those at high risk, so that prophylactic measure can be initiated before onset of overt disease.